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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P52564.1
Original Database ID EN ENSP00000468348.1
Organism Cercocebus atys, Cercocebus torquatus atys, etc.
Annotation mp2k6_human recname: full=dual
specificity mitogen-activated
protein kinase kina se 6; short=map
kinase kinase 6; short=mapkk 6;
altname: full=mapk/er ...
Sequence Length 334

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region44-333
Protein Length334
Template PDB Code3enmD
Template Region44-333
Sequence Identity99%
E-Value0
GA3411
MPQS2.04126
z-DOPE-1.31
TSVMod MethodMSALL
TSVMod RMSD0.983
TSVMod NO350.966
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB3enmthe structure of the map2k mek6 reveals an autoinhibitory dimer
DBALI3enmD 
JenaImageLibrary3enm 
Target Sequence
UniProtKBA8K3Y2SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|EMBL:ABY87539.1};SubName: Full=Mitogen-activated protein kinase kinase 6, isoform CRA_b {ECO:0000313|EMBL:EAW89085.1};SubName: Full
InterProA8K3Y2 
PFAMA8K3Y2 
ProdomA8K3Y2 
UniProtKBH2QZW5SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|EMBL:JAA33924.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000039686};
InterProH2QZW5 
PFAMH2QZW5 
ProdomH2QZW5 
UniProtKBP52564RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6;Short=MAP kinase kinase 6;Short=MAPKK 6;EC=2.7.12.2;AltName: Full=MAPK/ERK kinase 6;Short=MEK 6;AltName: Full=Stress-activated
InterProP52564 
PFAMP52564 
ProdomP52564 
UniProtKBA0A0D9QWI2SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000000721};
InterProA0A0D9QWI2 
PFAMA0A0D9QWI2 
ProdomA0A0D9QWI2 
UniProtKBH2NUJ7SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000009634};
InterProH2NUJ7 
PFAMH2NUJ7 
ProdomH2NUJ7 
UniProtKBF6QNB5SubName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000313|EMBL:AFE64198.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000001409};
InterProF6QNB5 
PFAMF6QNB5 
ProdomF6QNB5 
UniProtKBG3QTE4SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000005958};
InterProG3QTE4 
PFAMG3QTE4 
ProdomG3QTE4 
UniProtKBG1QQD5SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000003153};
InterProG1QQD5 
PFAMG1QQD5 
ProdomG1QQD5 
UniProtKBA0A096NU44SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000016565};
InterProA0A096NU44 
PFAMA0A096NU44 
ProdomA0A096NU44 
UniProtKBA0A8D2GCW6SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|Ensembl:ENSTGEP00000033282}
InterProA0A8D2GCW6 
PFAMA0A8D2GCW6 
ProdomA0A8D2GCW6 
UniProtKBA8K3Y2SubName: Full=Mitogen-activated protein kinase kinase 6;SubName: Full=Mitogen-activated protein kinase kinase 6, isoform CRA_b;SubName: Full=cDNA FLJ75671, highly similar to Homo sapiens mitogen-activ
InterProA8K3Y2 
PFAMA8K3Y2 
ProdomA8K3Y2 
UniProtKBA0A8C9LHH2SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|Ensembl:ENSPTEP00000002504}
InterProA0A8C9LHH2 
PFAMA0A8C9LHH2 
ProdomA0A8C9LHH2 
UniProtKBA0A6D2XRY6SubName: Full=MAP2K6 isoform 1 {ECO:0000313|EMBL:PNJ50983.1}
InterProA0A6D2XRY6 
PFAMA0A6D2XRY6 
ProdomA0A6D2XRY6 
UniProtKBA0A6D2WAD6SubName: Full=MAP2K6 isoform 1 {ECO:0000313|EMBL:PNI35630.1}
InterProA0A6D2WAD6 
PFAMA0A6D2WAD6 
ProdomA0A6D2WAD6 
UniProtKBA0A2I3LHS5SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|Ensembl:ENSPANP00000022973}
InterProA0A2I3LHS5 
PFAMA0A2I3LHS5 
ProdomA0A2I3LHS5 
UniProtKBA0A2J8KKV1SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|EMBL:JAA33924.1, ECO:0000313|Ensembl:ENSPTRP00000039686}
InterProA0A2J8KKV1 
PFAMA0A2J8KKV1 
ProdomA0A2J8KKV1 
UniProtKBA0A2J8V0E4SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000009634}
InterProA0A2J8V0E4 
PFAMA0A2J8V0E4 
ProdomA0A2J8V0E4 
UniProtKBA0A2K5WZY2Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5WZY2 
PFAMA0A2K5WZY2 
ProdomA0A2K5WZY2 
UniProtKBA0A2K5YG13Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5YG13 
PFAMA0A2K5YG13 
ProdomA0A2K5YG13 
UniProtKBA0A2K6CS09Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6CS09 
PFAMA0A2K6CS09 
ProdomA0A2K6CS09 
UniProtKBA0A2K6P656Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6P656 
PFAMA0A2K6P656 
ProdomA0A2K6P656 
UniProtKBA0A2R9BGH1Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2R9BGH1 
PFAMA0A2R9BGH1 
ProdomA0A2R9BGH1 
UniProtKBA0A2K6LB21Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6LB21 
PFAMA0A2K6LB21 
ProdomA0A2K6LB21 
UniProtKBF6QNB5SubName: Full=Dual specificity mitogen-activated protein kinase kinase 6;SubName: Full=Uncharacterized protein;
InterProF6QNB5 
PFAMF6QNB5 
ProdomF6QNB5 
UniProtKBA0A2K5P0S9Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5P0S9 
PFAMA0A2K5P0S9 
ProdomA0A2K5P0S9 
UniProtKBH2NUJ7SubName: Full=Uncharacterized protein;
InterProH2NUJ7 
PFAMH2NUJ7 
ProdomH2NUJ7 
UniProtKBG1QQD5SubName: Full=Uncharacterized protein;
InterProG1QQD5 
PFAMG1QQD5 
ProdomG1QQD5 
UniProtKBG3QTE4SubName: Full=Uncharacterized protein;
InterProG3QTE4 
PFAMG3QTE4 
ProdomG3QTE4 
UniProtKBH2QZW5SubName: Full=Uncharacterized protein;
InterProH2QZW5 
PFAMH2QZW5 
ProdomH2QZW5 
UniProtKBH9EP89SubName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000313|EMBL:AFE64198.1}SubName: Full=Mitogen-activated protein kinase kinase 6 {ECO:0000313|Ensembl:ENSMMUP00000001409}
InterProH9EP89 
PFAMH9EP89 
ProdomH9EP89 
UniProtKBP52564.1MP2K6_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=SAPKK3
InterProP52564.1 
PFAMP52564.1 
ProdomP52564.1 
UniProtKBP52564RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6;Short=MAP kinase kinase 6;Short=MAPKK 6;EC=2.7.12.2;AltName: Full=MAPK/ERK kinase 6;Short=MEK 6;AltName: Full=Stress-activated
InterProP52564 
PFAMP52564 
ProdomP52564 
RefSeqXP_028691299.1dual specificity mitogen-activated protein kinase kinase 6 isoform X1
RefSeqXP_025217836.1dual specificity mitogen-activated protein kinase kinase 6
RefSeqXP_023067716.1dual specificity mitogen-activated protein kinase kinase 6 isoform X1
RefSeqXP_008010158.2dual specificity mitogen-activated protein kinase kinase 6 isoform X1
RefSeqXP_032033849.1dual specificity mitogen-activated protein kinase kinase 6 isoform X1
RefSeqXP_002827807.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 6-like isoform 1 [Pongo abelii]
RefSeqXP_001083492.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 6-like [Macaca mulatta]
RefSeqXP_033037870.1dual specificity mitogen-activated protein kinase kinase 6 isoform X2
RefSeqNP_002749.2 dual specificity mitogen-activated protein kinase kinase 6 [Homo sapiens]
RefSeqXP_523699.2 PREDICTED: mitogen-activated protein kinase kinase 6 [Pan troglodytes]
GenPept60815137mitogen-activated protein kinase kinase 6
GenPept14773043 mitogen-activated protein kinase kinase 6 [Homo sapiens]
GenPept109117496 PREDICTED: dual specificity mitogen-activated protein kinase kinase 6-like [Macaca mulatta]
GenPept15080540Mitogen-activated protein kinase kinase 6
GenPept15102959Sequence 4 from patent US 6174676
GenPept15312650 mitogen-activated protein kinase kinase 6 [Homo sapiens]
GenPept158254930unnamed protein product
GenPept166706783mitogen-activated protein kinase kinase 6
GenPept168277608dual specificity mitogen-activated protein kinase kinase 6, partial
GenPept1709088MP2K6_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=SAPKK3
GenPept197692453mitogen-activated protein kinase kinase 6, partial
GenPept281079325Sequence 248 from patent US 7615626
GenPept1495485MAP kinase kinase
GenPept14773048 mitogen-activated protein kinase kinase 6, isoform 1 [Homo sapiens]
GenPept14589900 dual specificity mitogen-activated protein kinase kinase 6 [Homo sapiens]
GenPept114670209 PREDICTED: dual specificity mitogen-activated protein kinase kinase 6 [Pan troglodytes]
GenPept119609491mitogen-activated protein kinase kinase 6, isoform CRA_b
GenPept1203816MAP kinase kinase 6
GenPept1203818MAP kinase kinase 6
GenPept123995995mitogen-activated protein kinase kinase 6, partial
GenPept12740468 mitogen-activated protein kinase kinase 6, isoform 2 [Homo sapiens]
GenPept12808042Sequence 2 from patent US 6074862
GenPept1314477MAP kinase kinase MEK6
GenPept14477824Sequence 4 from patent US 6136596
GenPept123981170mitogen-activated protein kinase kinase 6
GenPept380784645dual specificity mitogen-activated protein kinase kinase 6
GenPept3991112AR000962 Sequence 4 from patent US 5736381
GenPept383411821dual specificity mitogen-activated protein kinase kinase 6
GenPept430152987Sequence 248 from patent US 8318137
GenPept31691335Sequence 4 from patent US 6541605
GenPept314264546Sequence 86 from patent US 7763425
GenPept297701631 PREDICTED: dual specificity mitogen-activated protein kinase kinase 6-like isoform 1 [Pongo abelii]
GenPept440503005mitogen-activated protein kinase kinase 6
GenPept53972175Sequence 1187 from patent US 6753314
GenPept568531816Sequence 13674 from patent US 8586006
GenPept61358117mitogen-activated protein kinase kinase 6
GenPept1596165mitogen-activated protein 6
GenPept649102476MAP2K6, partial
GenPept649151184MAP2K6, partial
GenPept7434332S71631 mitogen-activated protein kinase kinase (EC 2.7.1.-) 6 [similarity] - human
GenPept757002920Sequence 248 from patent US 8883425
GenPept40091394Sequence 4 from patent US 6610523
GenBankEAW89085.1 mitogen-activated protein kinase kinase 6, isoform CRA_b [Homo sapiens]
GenBankABM85599.1 mitogen-activated protein kinase kinase 6 [synthetic construct]
GenBankABY87539.1 mitogen-activated protein kinase kinase 6 [Homo sapiens]
GenBankABM82414.1 mitogen-activated protein kinase kinase 6 [synthetic construct]
GenBankAAX41506.1 mitogen-activated protein kinase kinase 6 [synthetic construct]
GenBankAAH12009.1 Mitogen-activated protein kinase kinase 6 [Homo sapiens]
GenBankAAC50389.1 MAP kinase kinase 6 [Homo sapiens]
GenBankAAC50388.1 MAP kinase kinase 6 [Homo sapiens]
GenBankAAX36333.1 mitogen-activated protein kinase kinase 6 [synthetic construct]
GenBankAAB05035.1 MAP kinase kinase MEK6 [Homo sapiens]
ENSEMBLENSP00000351997Dual specificity mitogen-activated protein kinase kinase 6 (EC 2.7.1.-) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3). [Homo sapiens]
EMBLCAA65532.1 
UCSCGenomeBrowserP52564 
ENSEMBLENSP00000351997 
ENSEMBLENSPTRP00000039686 
ENSEMBLENSP00000351997TDI sequence
ENSEMBLENSP00000468348