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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link P53778
Original Database ID sp P53778
Organism Homo sapiens, synthetic construct
Annotation recname: full=mitogen-activated
protein kinase 12;short=map kinase
12;short=mapk 12;ec=2.7.11.24;altname:
full=extracellular signal-regulated
kinase ...
Sequence Length 367

Dataset Information:

The newest dataset for this sequence was created on 2020-12-01. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region27-332
Protein Length367
Template PDB Code3i6uA
Template Region220-501
Sequence Identity25%
E-Value0
GA3410.47
MPQS0.821287
z-DOPE0.94
TSVMod MethodMSALL
TSVMod RMSD13.239
TSVMod NO350.294
DatasetMW-ch2
ModPipe VersionSVN.r1703
Model Date2020-12-01

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3i6ustructure and activation mechanism of the chk2 dna-damage checkpoint kinase
DBALI3i6uA 
JenaImageLibrary3i6u 
Target Sequence
UniProtKBQ99672RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ99672 
PFAMQ99672 
ProdomQ99672 
UniProtKBQ99588RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ99588 
PFAMQ99588 
ProdomQ99588 
UniProtKBP53778RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProP53778 
PFAMP53778 
ProdomP53778 
UniProtKBQ14260RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ14260 
PFAMQ14260 
ProdomQ14260 
UniProtKBP53778RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProP53778 
PFAMP53778 
ProdomP53778 
UniProtKBP53778.3MK12_HUMAN RecName: Full=Mitogen-activated protein kinase 12; Short=MAP kinase 12; Short=MAPK 12; AltName: Full=Extracellular signal-regulated kinase 6; Short=ERK-6; AltName: Full=Mitogen-activated pr
InterProP53778.3 
PFAMP53778.3 
ProdomP53778.3 
UniProtKBQ14260RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ14260 
PFAMQ14260 
ProdomQ14260 
UniProtKBQ6IC53RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ6IC53 
PFAMQ6IC53 
ProdomQ6IC53 
UniProtKBQ99588RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ99588 
PFAMQ99588 
ProdomQ99588 
UniProtKBQ99672RecName: Full=Mitogen-activated protein kinase 12;Short=MAP kinase 12;Short=MAPK 12;EC=2.7.11.24;AltName: Full=Extracellular signal-regulated kinase 6;Short=ERK-6;AltName: Full=Mitogen-activated prote
InterProQ99672 
PFAMQ99672 
ProdomQ99672 
RefSeqNP_002960.2 mitogen-activated protein kinase 12 [Homo sapiens]
GenPept756202196Sequence 32 from patent US 8673268
GenPept649151225MAPK12, partial
GenPept649121088MAPK12, partial
GenPept5629911mitogen-activated protein kinase 12
GenPept53972191Sequence 1203 from patent US 6753314
GenPept48255970 mitogen-activated protein kinase 12 [Homo sapiens]
GenPept1785656stress-activated protein kinase-3
GenPept16041727Mitogen-activated protein kinase 12
GenPept155076311Sequence 24 from patent US 7202033
GenPept14779850 stress-activated protein kinase 3 [Homo sapiens]
GenPept14779847 stress-activated protein kinase 3 [Homo sapiens]
GenPept13630200 stress-activated protein kinase 3 [Homo sapiens]
GenPept123998809mitogen-activated protein kinase 12, partial
GenPept123985226mitogen-activated protein kinase 12
GenPept21512944Sequence 1 from patent US 6387641
GenPept21512984Sequence 33 from patent US 6387641
GenPept119593928mitogen-activated protein kinase 12, isoform CRA_b
GenPept397017754Sequence 32 from patent US 8097408
GenPept2851522MK12_HUMAN RecName: Full=Mitogen-activated protein kinase 12; Short=MAP kinase 12; Short=MAPK 12; AltName: Full=Extracellular signal-regulated kinase 6; Short=ERK-6; AltName: Full=Mitogen-activated pr
GenPept223622011Sequence 32 from patent US 7485468
GenBankAAH15741.1 Mitogen-activated protein kinase 12 [Homo sapiens]
GenBankABM83713.1 mitogen-activated protein kinase 12 [synthetic construct]
GenBankABM87033.1 mitogen-activated protein kinase 12 [synthetic construct]
GenBankEAW73522.1 mitogen-activated protein kinase 12, isoform CRA_b [Homo sapiens]
ENSEMBLENSP00000215659Mitogen-activated protein kinase 12 (EC 2.7.1.37) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase-3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase
EMBLCAA71511.1 
ENSEMBLENSP00000215659 
ENSEMBLENSP00000215659TDI sequence
ENSEMBLENSP00000215659 
UCSCGenomeBrowserP53778