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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link Q15797.1
Original Database ID EN ENSP00000305769.4
Organism Cebus apella, Cercocebus atys, etc.
Annotation smad1_human recname: full=mothers
against decapentaplegic homolog
1; short=mad h omolog 1; short=mothers
against dpp homolog 1; altname:
full=jv4-1; a ...
Sequence Length 465

Dataset Information:

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Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

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Target Region267-465
Protein Length465
Template PDB Code3gmjD
Template Region257-455
Sequence Identity87%
E-Value0
GA3411
MPQS1.55086
z-DOPE-1.6
TSVMod MethodMSALL
TSVMod RMSD0.81
TSVMod NO350.949
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3gmjcrystal structure of mad mh2 domain
DBALI3gmjD 
CATH2.60.200.10 Domain: 3gmjD00 Tumour Suppressor Smad4 (100%)
JenaImageLibrary3gmj 
Target Sequence
UniProtKBQ16636RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProQ16636 
PFAMQ16636 
ProdomQ16636 
UniProtKBA8KAJ0RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProA8KAJ0 
PFAMA8KAJ0 
ProdomA8KAJ0 
UniProtKBD3DNZ9RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProD3DNZ9 
PFAMD3DNZ9 
ProdomD3DNZ9 
UniProtKBF7GZL6RecName: Full=Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195};Short=MAD homolog {ECO:0000256|RuleBase:RU361195};Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195
InterProF7GZL6 
PFAMF7GZL6 
ProdomF7GZL6 
UniProtKBQ15797RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProQ15797 
PFAMQ15797 
ProdomQ15797 
UniProtKBG7P6D2RecName: Full=Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195};Short=MAD homolog {ECO:0000256|RuleBase:RU361195};Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195
InterProG7P6D2 
PFAMG7P6D2 
ProdomG7P6D2 
UniProtKBA0A2K5INL5Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K5INL5 
PFAMA0A2K5INL5 
ProdomA0A2K5INL5 
UniProtKBA0A2K6UM26Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K6UM26 
PFAMA0A2K6UM26 
ProdomA0A2K6UM26 
UniProtKBA0A2K6RAP1Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K6RAP1 
PFAMA0A2K6RAP1 
ProdomA0A2K6RAP1 
UniProtKBA0A2K6L070Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K6L070 
PFAMA0A2K6L070 
ProdomA0A2K6L070 
UniProtKBA0A2K6B401Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K6B401 
PFAMA0A2K6B401 
ProdomA0A2K6B401 
UniProtKBA0A2K5YVF0Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K5YVF0 
PFAMA0A2K5YVF0 
ProdomA0A2K5YVF0 
UniProtKBG7P6D2SubName: Full=Putative uncharacterized protein;
InterProG7P6D2 
PFAMG7P6D2 
ProdomG7P6D2 
UniProtKBA0A2K5WIT6Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K5WIT6 
PFAMA0A2K5WIT6 
ProdomA0A2K5WIT6 
UniProtKBF7GZM0Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProF7GZM0 
PFAMF7GZM0 
ProdomF7GZM0 
UniProtKBF7GZL6SubName: Full=Mothers against decapentaplegic homolog 1;SubName: Full=Uncharacterized protein;
InterProF7GZL6 
PFAMF7GZL6 
ProdomF7GZL6 
UniProtKBA0A2K5RHV7Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K5RHV7 
PFAMA0A2K5RHV7 
ProdomA0A2K5RHV7 
UniProtKBA0A2K5NE45Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A2K5NE45 
PFAMA0A2K5NE45 
ProdomA0A2K5NE45 
UniProtKBA0A6J3FA87Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A6J3FA87 
PFAMA0A6J3FA87 
ProdomA0A6J3FA87 
UniProtKBA0A8C9G875SubName: Full=SMAD family member 1 {ECO:0000313|Ensembl:ENSPTEP00000000119}
InterProA0A8C9G875 
PFAMA0A8C9G875 
ProdomA0A8C9G875 
UniProtKBA0A1D5Q7V1Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A1D5Q7V1 
PFAMA0A1D5Q7V1 
ProdomA0A1D5Q7V1 
UniProtKBD3DNZ9SubName: Full=SMAD, mothers against DPP homolog 1 (Drosophila), isoform CRA_a;
InterProD3DNZ9 
PFAMD3DNZ9 
ProdomD3DNZ9 
UniProtKBA0A8D2F3Q0SubName: Full=SMAD family member 1 {ECO:0000313|Ensembl:ENSTGEP00000015352}
InterProA0A8D2F3Q0 
PFAMA0A8D2F3Q0 
ProdomA0A8D2F3Q0 
UniProtKBG7MS28SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH26222.1}
InterProG7MS28 
PFAMG7MS28 
ProdomG7MS28 
UniProtKBA0A8J8XS88Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}Short=MAD homolog {ECO:0000256|RuleBase:RU361195}Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}AltName: Full=S
InterProA0A8J8XS88 
PFAMA0A8J8XS88 
ProdomA0A8J8XS88 
UniProtKBA8KAJ0SubName: Full=cDNA FLJ75507, highly similar to Homo sapiens SMAD, mothers against DPP homolog 1 (Drosophila) (SMAD1), transcript variant 2, mRNA;SubName: Full=SMAD, mothers against DPP homolog 1 (Dros
InterProA8KAJ0 
PFAMA8KAJ0 
ProdomA8KAJ0 
UniProtKBD3DNZ9RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProD3DNZ9 
PFAMD3DNZ9 
ProdomD3DNZ9 
UniProtKBQ15797RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProQ15797 
PFAMQ15797 
ProdomQ15797 
UniProtKBA8KAJ0RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProA8KAJ0 
PFAMA8KAJ0 
ProdomA8KAJ0 
UniProtKBQ9UFT8RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProQ9UFT8 
PFAMQ9UFT8 
ProdomQ9UFT8 
UniProtKBQ16636RecName: Full=Mothers against decapentaplegic homolog 1;Short=MAD homolog 1;Short=Mothers against DPP homolog 1;AltName: Full=JV4-1;AltName: Full=Mad-related protein 1;AltName: Full=SMAD family member
InterProQ16636 
PFAMQ16636 
ProdomQ16636 
UniProtKBQ15797.1SMAD1_HUMAN RecName: Full=Mothers against decapentaplegic homolog 1; Short=MAD homolog 1; Short=Mothers against DPP homolog 1; AltName: Full=JV4-1; AltName: Full=Mad-related protein 1; AltName: Full=S
InterProQ15797.1 
PFAMQ15797.1 
ProdomQ15797.1 
RefSeqXP_025241665.1mothers against decapentaplegic homolog 1
RefSeqXP_033071283.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_033071282.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_025241666.1mothers against decapentaplegic homolog 1
RefSeqNP_001341743.1mothers against decapentaplegic homolog 1
RefSeqXP_025241667.1mothers against decapentaplegic homolog 1
RefSeqXP_003899285.1mothers against decapentaplegic homolog 1
RefSeqXP_007998093.2mothers against decapentaplegic homolog 1
RefSeqXP_007998095.2mothers against decapentaplegic homolog 1
RefSeqXP_017814576.1mothers against decapentaplegic homolog 1
RefSeqXP_017814577.1mothers against decapentaplegic homolog 1
RefSeqXP_023082836.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_023082844.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_023082851.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_003899284.1mothers against decapentaplegic homolog 1
RefSeqXP_025241662.1mothers against decapentaplegic homolog 1
RefSeqNP_005891.1 mothers against decapentaplegic homolog 1 [Homo sapiens]
RefSeqXP_025241663.1mothers against decapentaplegic homolog 1
RefSeqXP_009205911.1mothers against decapentaplegic homolog 1
RefSeqNP_001003688.1 mothers against decapentaplegic homolog 1 [Homo sapiens]
RefSeqNP_001341740.1mothers against decapentaplegic homolog 1
RefSeqNP_001341741.1mothers against decapentaplegic homolog 1
RefSeqNP_001341742.1mothers against decapentaplegic homolog 1
RefSeqNP_001341745.1mothers against decapentaplegic homolog 1
RefSeqNP_001341746.1mothers against decapentaplegic homolog 1
RefSeqXP_025241661.1mothers against decapentaplegic homolog 1
RefSeqXP_033071281.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_033071280.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_037848541.1mothers against decapentaplegic homolog 1
RefSeqXP_039335063.1mothers against decapentaplegic homolog 1
RefSeqXP_037848543.1mothers against decapentaplegic homolog 1
RefSeqXP_039335064.1mothers against decapentaplegic homolog 1
RefSeqXP_037596476.1mothers against decapentaplegic homolog 1
RefSeqXP_001096679.1 PREDICTED: mothers against decapentaplegic homolog 1 [Macaca mulatta]
RefSeqXP_033071278.1mothers against decapentaplegic homolog 1 isoform X1
RefSeqXP_025241664.1mothers against decapentaplegic homolog 1
RefSeqXP_030777856.1mothers against decapentaplegic homolog 1
RefSeqXP_030777862.1mothers against decapentaplegic homolog 1
RefSeqXP_033071279.1mothers against decapentaplegic homolog 1 isoform X1
GenPept1438077Smad1
GenPept1469308transforming growth factor-beta signaling protein-1
GenPept14730067 MAD (mothers against decapentaplegic, Drosophila) homolog 1 [Homo sapiens]
GenPept14730084 MAD (mothers against decapentaplegic, Drosophila) homolog 1 [Homo sapiens]
GenPept14730071 MAD (mothers against decapentaplegic, Drosophila) homolog 1 [Homo sapiens]
GenPept13633915SMAD1_HUMAN RecName: Full=Mothers against decapentaplegic homolog 1; Short=MAD homolog 1; Short=Mothers against DPP homolog 1; AltName: Full=JV4-1; AltName: Full=Mad-related protein 1; AltName: Full=S
GenPept1332714mad-related protein MADR1
GenPept12804861SMAD family member 1
GenPept123998097SMAD, mothers against DPP homolog 1 (Drosophila), partial
GenPept123983390SMAD, mothers against DPP homolog 1 (Drosophila)
GenPept119625445SMAD, mothers against DPP homolog 1 (Drosophila), isoform CRA_a
GenPept119625442SMAD, mothers against DPP homolog 1 (Drosophila), isoform CRA_a
GenPept109075809 PREDICTED: mothers against decapentaplegic homolog 1 [Macaca mulatta]
GenPept355687638hypothetical protein EGK_16135
GenPept16236371Sequence 6 from patent US 6270994
GenPept649101284SMAD1, partial
GenPept51173727 mothers against decapentaplegic homolog 1 [Homo sapiens]
GenPept384947048mothers against decapentaplegic homolog 1
GenPept383418393mothers against decapentaplegic homolog 1
GenPept380783641mothers against decapentaplegic homolog 1
GenPept355749601hypothetical protein EGM_14729
GenPept331495449Sequence 25 from patent US 7901874
GenPept315458011unnamed protein product
GenPept314264505Sequence 4 from patent US 7763425
GenPept30583611MAD, mothers against decapentaplegic homolog 1 (Drosophila)
GenPept259251318Sequence 6 from patent US 7560532
GenPept239681946Sequence 32 from patent US 7537902
GenPept2136167S68987 transcription activator Smad1 - human
GenPept1654323Smad1
ENSEMBLENSP00000305769 
ENSEMBLENSP00000305769TDI sequence
ENSEMBLENSP00000305769 
UCSCGenomeBrowserQ15797