| |
| TARGET | MODEL DATA | TEMPLATE |
|---|
Model
Icon | Model/Fold
Reliability | Sequence
Database
Link | Database Annotation | Organism | Protein
Size | Modeled
Segment | Size | Seq
Id(%) | PDB
code | PDB
Segment | PDB Comment |
|---|
 |  | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1230 | 279 | 7 | 1ob3A | 1-246 | structure of p. falciparum
pfpk5 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 954-1260 | 307 | 7 | 1z57A | 160-457 | crystal structure of
human clk1 in complex
with 10z-hymenialdisine |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 3-44 | 42 | 7 | 2proA | 5-46 | pro region of alpha-lytic
protease |
 |  | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1341-1607 | 267 | 34 | 1f3mC | 269-528 | crystal structure of
human serine/threonine
kinase pak1 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 955-1215 | 261 | 8 | 1xkkA | 712-950 | egfr kinase domain complexed
with a quinazoline inhibitor-
gw572016 |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 345-1165 | 821 | 12 | 3m62A | 38-855 | crystal structure of
ufd2 in complex with
the ubiquitin-like (ubl)
domain of rad23 |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1343-1602 | 260 | 28 | 3c0gB | 12-277 | cask cam-kinase domain-
3'-amp complex, p1 form |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1342-1601 | 260 | 26 | 3cokA | 10-264 | crystal structure of
plk4 kinase |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 955-1195 | 241 | 6 | 1j1bA | 56-271 | binary complex structure
of human tau protein
kinase i with amppnp |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 948-1269 | 322 | 7 | 1vzoA | 42-344 | the structure of the
n-terminal kinase
domain of msk1 reveals
a novel autoinhibitory
conformation for a dual
kinase protein |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 959-1226 | 268 | 5 | 1xbbA | 375-619 | crystal structure of
the syk tyrosine kinase
domain with gleevec |
 |  | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1507-1589 | 83 | 33 | 3repA | 354-436 | |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1445-1545 | 101 | 43 | 2h34A | 121-215 | apoenzyme crystal structure
of the tuberculosis
serine/threonine kinase,
pkne |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 941-1348 | 408 | 7 | 1koa | 5929-6310 | twitchin kinase fragment
(c.elegans), autoregulated
protein kinase and immunoglobulin
domains |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 951-1276 | 326 | 7 | 1fotA | 83-390 | structure of the unliganded
camp-dependent protein
kinase catalytic subunit
from saccharomyces cerevisiae |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1222-1607 | 386 | 18 | 1omwA | 70-460 | crystal structure of
the complex between
g protein-coupled receptor
kinase 2 and heterotrimeric
g protein beta 1 and
gamma 2 subunits |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 953-1194 | 242 | 5 | 1blxA | 11-232 | p19ink4d/cdk6 complex |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 4-44 | 41 | 7 | 3proC | 28-68 | alpha-lytic protease
complexed with c-terminal
truncated pro region |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1229-1608 | 380 | 22 | 4y93A | 68-658 | |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1229 | 278 | 9 | 1k2pA | 399-646 | crystal structure of
bruton's tyrosine kinase
domain |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1340-1599 | 260 | 27 | 1x8bA | 296-567 | structure of human wee1a
kinase: kinase domain
complexed with inhibitor
pd0407824 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 951-1238 | 288 | 6 | 1ia8A | 5-268 | the 1.7 a crystal structure
of human cell cycle
checkpoint kinase chk1 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 953-1235 | 283 | 6 | 1s9jA | 66-361 | x-ray structure of the
human mitogen-activated
protein kinase kinase
1 (mek1) in a complex
with ligand and mgatp |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1006-1225 | 220 | 7 | 1cm8A | 52-275 | phosphorylated map kinase
p38-gamma |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 951-1236 | 286 | 7 | 1oiuC | 0-287 | structure of human thr160-phospho
cdk2/cyclin a complexed
with a 6-cyclohexylmethyloxy-2-anilino-purine
inhibitor |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 953-1195 | 243 | 7 | 1ymiA | 37-247 | |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1229 | 278 | 7 | 1p4oA | 966-1232 | structure of apo unactivated
igf-1r kinase domain
at 1.5a resolution. |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 939-1229 | 291 | 7 | 1t46A | 573-920 | structural basis for
the autoinhibition and
sti-571 inhibition of
c-kit tyrosine kinase |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1227-1601 | 375 | 20 | 1omwA | 88-454 | crystal structure of
the complex between
g protein-coupled receptor
kinase 2 and heterotrimeric
g protein beta 1 and
gamma 2 subunits |
 |  | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1342-1602 | 261 | 15 | 3ckxA | 8-260 | crystal structure of
sterile 20-like kinase
3 (mst3, stk24) in complex
with staurosporine |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1210-1596 | 387 | 20 | 5mo4A | 132-509 | |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1194 | 243 | 7 | 1pmnA | 61-276 | crystal structure of
jnk3 in complex with
an imidazole-pyrimidine
inhibitor |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 831-938 | 108 | 9 | 1unqA | 17-117 | high resolution crystal
structure of the pleckstrin
homology domain of protein
kinase b/akt bound to
ins(1,3,4,5)-tetrakisphophate |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1204-1595 | 392 | 18 | 1fmk | 133-513 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1195 | 244 | 6 | 1unlA | 1-217 | structural mechanism
for the inhibition of
cd5-p25 from the roscovitine,
aloisine and indirubin. |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 831-922 | 92 | 18 | 1p6sA | 17-101 | solution structure of
the pleckstrin homology
domain of human protein
kinase b beta (pkb/akt) |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1224-1607 | 384 | 18 | 1omwA | 69-460 | crystal structure of
the complex between
g protein-coupled receptor
kinase 2 and heterotrimeric
g protein beta 1 and
gamma 2 subunits |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1333-1606 | 274 | 26 | 1jksA | 4-294 | 1.5a x-ray structure
of apo form of a catalytic
domain of death-associated
protein kinase |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 960-1215 | 256 | 7 | 1u59A | 343-575 | crystal structure of
the zap-70 kinase domain
in complex with staurosporine |
 | | Q9Y6R4.2 | m3k4_human recname: full=mitogen-activated
protein kinase kinase kinase
4; altna me: full=map three
kinase 1; altname: full=mapk/erk
kinase kinase 4; short=mek
kinase 4; short=mekk 4 | Homo sapiens | 1608 | 1346-1601 | 256 | 32 | 3cokA | 14-264 | crystal structure of
plk4 kinase |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1239 | 288 | 9 | 1o6yA | 8-278 | catalytic domain of
pknb kinase from mycobacterium
tuberculosis |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 950-1229 | 280 | 6 | 1qpcA | 240-490 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1007-1194 | 188 | 6 | 1pme | 53-241 | structure of penta mutant
human erk2 map kinase
complexed with a specific
inhibitor of human p38
map kinase |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 952-1258 | 307 | 7 | 1xjdA | 377-696 | crystal structure of
pkc-theta complexed
with staurosporine at
2a resolution |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 953-1254 | 302 | 8 | 1ckiA | 10-299 | recombinant casein kinase
i delta truncation mutant
containing residues
1-317 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 953-1242 | 290 | 6 | 1phk | 17-290 | two structures of the
catalytic domain of
phosphorylase, kinase:
an active protein kinase
complexed with nucleotide,
substrate-analogue and
product |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1315-1602 | 288 | 24 | 1kobA | 26-310 | twitchin kinase fragment
(aplysia), autoregulated
protein kinase domain |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1259-1606 | 348 | 20 | 1omwA | 108-459 | crystal structure of
the complex between
g protein-coupled receptor
kinase 2 and heterotrimeric
g protein beta 1 and
gamma 2 subunits |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 951-1217 | 267 | 6 | 1rjbA | 606-926 | crystal structure of
flt3 |
 | | Q92612 | recname: full=mitogen-activated
protein kinase kinase kinase
4;ec=2.7.11.25;altn ame:
full=mapk/erk kinase kinase
4;short=mek kinase 4;short=mekk
4;altname: full=map three
kinase 1; | Homo sapiens | 1607 | 1324-1601 | 278 | 26 | 1koa | 5924-6198 | twitchin kinase fragment
(c.elegans), autoregulated
protein kinase and immunoglobulin
domains |
