| |
| TARGET | MODEL DATA | TEMPLATE |
|---|
Model
Icon | Model/Fold
Reliability | Sequence
Database
Link | Database Annotation | Organism | Protein
Size | Modeled
Segment | Size | Seq
Id(%) | PDB
code | PDB
Segment | PDB Comment |
|---|
 |  | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 64-505 | 442 | 72 | 1qcfA | 85-529 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 64-501 | 438 | 59 | 1fmk | 85-524 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 23-498 | 476 | 36 | 4fl2A | 89-630 | |
 |  | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 63-508 | 446 | 42 | 1opkA | 83-527 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 64-507 | 444 | 72 | 1qcfA | 84-530 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 240-498 | 259 | 53 | 2zv7A | 242-501 | lyn tyrosine kinase
domain, apo form |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 65-506 | 442 | 72 | 1qcfA | 85-529 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 50-498 | 449 | 28 | 2fo0A | 68-516 | organization of the
sh3-sh2 unit in active
and inactive forms of
the c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 62-121 | 60 | 55 | 1w1fA | 9-68 | sh3 domain of human
lyn tyrosine kinase |
 |  | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 36-494 | 459 | 14 | 2shpA | 19-516 | tyrosine phosphatase
shp-2 |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 9-167 | 159 | 15 | 1ng2A | 179-330 | structure of autoinhibited
p47phox |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 65-502 | 438 | 59 | 1fmk | 85-524 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 43-504 | 462 | 24 | 2j0kA | 189-686 | crystal structure of
a fragment of focal
adhesion kinase containing
the ferm and kinase
domains. |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 9-185 | 177 | 12 | 1ng2A | 179-332 | structure of autoinhibited
p47phox |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 63-508 | 446 | 42 | 1opkA | 83-527 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 23-225 | 203 | 33 | 1a81A | 89-260 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 22-495 | 474 | 26 | 2ozoA | 75-594 | autoinhibited intact
human zap-70 |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 36-494 | 459 | 15 | 2shpA | 19-516 | tyrosine phosphatase
shp-2 |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 23-498 | 476 | 36 | 4fl2A | 89-630 | |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 124-226 | 103 | 51 | 1kc2A | 147-249 | structure of the triple
(lys(beta)d3ala, asp(beta)c8ala,
aspcd2ala) mutant of
the src sh2 domain bound
to the pqpyeeipi peptide |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 6-185 | 180 | 13 | 1ng2A | 176-332 | structure of autoinhibited
p47phox |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 64-508 | 445 | 72 | 1qcfA | 85-531 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 40-508 | 469 | 41 | 2fo0A | 66-528 | organization of the
sh3-sh2 unit in active
and inactive forms of
the c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 406-498 | 93 | 100 | 2ofvA | 406-498 | crystal structure of
aminoquinazoline 1 bound
to lck |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 65-506 | 442 | 72 | 1qcfA | 85-529 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 62-503 | 442 | 72 | 1qcfA | 83-526 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 63-508 | 446 | 42 | 1opkA | 83-527 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 114-225 | 112 | 24 | 2knoA | 9-130 | nmr solution structure
of sh2 domain of the
human tensin like c1
domain containing phosphatase
(tenc1) |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 10-168 | 159 | 15 | 1ng2A | 179-330 | structure of autoinhibited
p47phox |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 241-490 | 250 | 15 | 3ckxA | 5-253 | crystal structure of
sterile 20-like kinase
3 (mst3, stk24) in complex
with staurosporine |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 23-498 | 476 | 36 | 4fl2A | 89-630 | |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 65-506 | 442 | 72 | 1qcfA | 85-529 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 63-506 | 444 | 72 | 1qcfA | 84-530 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 231-502 | 272 | 100 | 1qpcA | 231-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 6-509 | 504 | 26 | 2ozoA | 39-608 | autoinhibited intact
human zap-70 |
 |  | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 78-111 | 34 | 41 | 1x6gA | 32-67 | solution structures
of the sh3 domain of
human megakaryocyte-associated
tyrosine-protein kinase. |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 230-501 | 272 | 100 | 3bysA | 230-501 | co-crystal structure
of lck and aminopyrimidine
amide 10b |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 64-509 | 446 | 54 | 1fmk | 84-532 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 6-168 | 163 | 14 | 1ng2A | 176-331 | structure of autoinhibited
p47phox |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 30-499 | 470 | 30 | 1k9aA | 7-445 | crystal structure analysis
of full-length carboxyl-terminal
src kinase at 2.5 a
resolution |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 406-502 | 97 | 100 | 1qpcA | 406-502 | structural analysis
of the lymphocyte-specific
kinase lck in complex
with non-selective and
src family selective
kinase inhibitors |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 61-505 | 445 | 58 | 1fmk | 82-529 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 119-227 | 109 | 39 | 3eazA | 74-174 | crystal structure of
sh2 domain of human
csk (carboxyl-terminal
src kinase), c122s mutant. |
 | | 33757623 | sequence 1 from patent us
6589758 | Homo sapiens | 508 | 63-508 | 446 | 42 | 1opkA | 83-527 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P06239.6 | lck_human recname: full=tyrosine-protein
kinase lck; altname: full=lsk;
altname: full=lymphocyte
cell-specific protein-tyrosine
kinase; altname: full=proto-oncogene
lck; altname: full=t cell-specific | Gorilla gorilla gorilla,
Pan paniscus, etc. | 509 | 230-501 | 272 | 100 | 3bysA | 230-501 | co-crystal structure
of lck and aminopyrimidine
amide 10b |
