| |
| TARGET | MODEL DATA | TEMPLATE |
|---|
Model
Icon | Model/Fold
Reliability | Sequence
Database
Link | Database Annotation | Organism | Protein
Size | Modeled
Segment | Size | Seq
Id(%) | PDB
code | PDB
Segment | PDB Comment |
|---|
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 423-596 | 174 | 9 | 1g8xA | 827-1002 | structure of a genetically
engineered molecular
motor |
 |  | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 322-598 | 277 | 100 | 4l23B | 322-598 | |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 327-720 | 394 | 21 | 1a81A | 9-261 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-285 | 171 | 100 | 1pbwA | 115-285 | structure of bcr-homology
(bh) domain |
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 559-724 | 166 | 22 | 1qcfA | 86-251 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 321-431 | 111 | 97 | 1fu5A | 1-111 | nmr structure of the
n-sh2 domain of the
p85 subunit of pi3-kinase
complexed to a doubly
phosphorylated peptide
derived from polyomavirus
middle t antigen |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 71-294 | 224 | 26 | 2qv2A | 122-333 | a role of the lowe syndrome
protein ocrl in early
steps of the endocytic
pathway |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 293-429 | 137 | 23 | 1lckA | 87-225 | sh3-sh2 domain fragment
of human p56-lck tyrosine
kinase complexed with
the 10 residue synthetic
phosphotyrosyl peptide
tegqpyqpqpa |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 502-718 | 217 | 16 | 1m61A | 40-254 | crystal structure of
the apo sh2 domains
of zap-70 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 324-433 | 110 | 99 | 2iugA | 3-112 | crystal structure of
the pi3-kinase p85 n-terminal
sh2 domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 331-654 | 324 | 73 | 4yknA | 331-1078 | |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 89-287 | 199 | 21 | 1rgp | 36-227 | gtpase-activation domain
from rhogap |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 617-720 | 104 | 100 | 1h9oA | 5-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 451-720 | 270 | 76 | 2y3aB | 442-712 | |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 570-717 | 148 | 24 | 2shpA | 53-215 | tyrosine phosphatase
shp-2 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 431-600 | 170 | 99 | 2v1yB | 431-600 | structure of a phosphoinositide
3-kinaase alpha adaptor-binding
domain (abd) in a complex
with the ish2 domain
from p85 alpha |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 616-721 | 106 | 99 | 1h9oA | 4-109 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 646-718 | 73 | 24 | 3pqzA | 455-527 | |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 616-720 | 105 | 99 | 1h9oA | 4-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 71-294 | 224 | 26 | 2qv2A | 122-333 | a role of the lowe syndrome
protein ocrl in early
steps of the endocytic
pathway |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 2-82 | 81 | 100 | 3i5rA | 2-82 | pi3k sh3 domain in complex
with a peptide ligand |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 614-720 | 107 | 100 | 5aulA | 614-720 | |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 597-718 | 122 | 29 | 2abl | 119-236 | sh3-sh2 domain fragment
of human bcr-abl tyrosine
kinase |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 326-579 | 254 | 100 | 3hhmB | 326-579 | crystal structure of
p110alpha h1047r mutant
in complex with nish2
of p85alpha and the
drug wortmannin |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 80-294 | 215 | 20 | 3qisA | 654-896 | |
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 327-719 | 393 | 21 | 1m61A | 4-255 | crystal structure of
the apo sh2 domains
of zap-70 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 327-720 | 394 | 26 | 1a81A | 9-261 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 327-534 | 208 | 15 | 1a81A | 9-208 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 552-717 | 166 | 24 | 1g83A | 94-245 | crystal structure of
fyn sh3-sh2 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 319-429 | 111 | 24 | 2knoA | 8-130 | nmr solution structure
of sh2 domain of the
human tensin like c1
domain containing phosphatase
(tenc1) |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 382-715 | 334 | 10 | 2nrjA | 4-335 | crystal structure of
hemolysin binding component
from bacillus cereus |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 3-78 | 76 | 100 | 1pht | 3-78 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 215-430 | 216 | 19 | 1a81E | 21-261 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 3-85 | 83 | 100 | 1phtA | 3-85 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 326-579 | 254 | 100 | 3hhmB | 326-579 | crystal structure of
p110alpha h1047r mutant
in complex with nish2
of p85alpha and the
drug wortmannin |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 616-721 | 106 | 99 | 1h9oA | 4-109 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 431-600 | 170 | 99 | 2v1yB | 431-600 | structure of a phosphoinositide
3-kinaase alpha adaptor-binding
domain (abd) in a complex
with the ish2 domain
from p85 alpha |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 2-86 | 85 | 46 | 2dilA | 5-67 | solution structure of
the sh3 domain of the
human proline-serine-threonine
phosphatase-interacting
protein 1 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 1-298 | 298 | 17 | 2qv2A | 23-335 | a role of the lowe syndrome
protein ocrl in early
steps of the endocytic
pathway |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 688-724 | 37 | 46 | 3hhmB | 398-435 | crystal structure of
p110alpha h1047r mutant
in complex with nish2
of p85alpha and the
drug wortmannin |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 610-722 | 113 | 22 | 1mw4A | 5-119 | solution structure of
the human grb7-sh2 domain
in complex with a 10
amino acid peptide py1139 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 7-215 | 209 | 16 | 1qcfA | 85-272 | crystal structure of
hck in complex with
a src family-selective
tyrosine kinase inhibitor |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 586-710 | 125 | 34 | 2ptkA | 103-237 | chicken src tyrosine
kinase |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 272-429 | 158 | 20 | 1lckA | 69-225 | sh3-sh2 domain fragment
of human p56-lck tyrosine
kinase complexed with
the 10 residue synthetic
phosphotyrosyl peptide
tegqpyqpqpa |
