| |
| TARGET | MODEL DATA | TEMPLATE |
|---|
Model
Icon | Model/Fold
Reliability | Sequence
Database
Link | Database Annotation | Organism | Protein
Size | Modeled
Segment | Size | Seq
Id(%) | PDB
code | PDB
Segment | PDB Comment |
|---|
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 313-438 | 126 | 26 | 2crhA | 8-132 | solution structure of
the sh2 domain of human
proto-oncogene protein
vav1 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 331-654 | 324 | 73 | 4yknA | 331-1078 | |
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 1-105 | 105 | 20 | 1ng2A | 224-308 | structure of autoinhibited
p47phox |
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 327-466 | 140 | 15 | 1uurA | 581-705 | structure of an activated
dictyostelium stat in
its dna-unbound form |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 559-723 | 165 | 25 | 1opkA | 85-241 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 595-718 | 124 | 28 | 2abl | 117-236 | sh3-sh2 domain fragment
of human bcr-abl tyrosine
kinase |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 431-600 | 170 | 99 | 2v1yB | 431-600 | structure of a phosphoinositide
3-kinaase alpha adaptor-binding
domain (abd) in a complex
with the ish2 domain
from p85 alpha |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 325-439 | 115 | 99 | 2iuhA | 4-118 | crystal structure of
the pi3-kinase p85 n-terminal
sh2 domain in complex
with c-kit phosphotyrosyl
peptide |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 1-84 | 84 | 99 | 1pnj | 1-84 | solution structure and
ligand-binding site
of the sh3 domain of
the p85alpha subunit
of phosphatidylinositol
3-kinase |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 615-720 | 106 | 98 | 1h9oA | 3-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 |  | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 513-720 | 208 | 18 | 1a81A | 57-261 | crystal structure of
the tandem sh2 domain
of the syk kinase bound
to a dually tyrosine-phosphorylated
itam |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 2-102 | 101 | 29 | 1uffA | 2-87 | solution structure of
the first sh3 domain
of human intersectin2
(kiaa1256) |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 322-598 | 277 | 100 | 4l23B | 322-598 | |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 617-720 | 104 | 100 | 1h9oA | 5-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 2-106 | 105 | 28 | 1uffA | 2-91 | solution structure of
the first sh3 domain
of human intersectin2
(kiaa1256) |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 549-719 | 171 | 24 | 2abl | 75-237 | sh3-sh2 domain fragment
of human bcr-abl tyrosine
kinase |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 52-305 | 254 | 20 | 1xa6A | 161-466 | crystal structure of
the human beta2-chimaerin |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 327-431 | 105 | 97 | 1fu5A | 7-111 | nmr structure of the
n-sh2 domain of the
p85 subunit of pi3-kinase
complexed to a doubly
phosphorylated peptide
derived from polyomavirus
middle t antigen |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 272-429 | 158 | 20 | 1lckA | 69-225 | sh3-sh2 domain fragment
of human p56-lck tyrosine
kinase complexed with
the 10 residue synthetic
phosphotyrosyl peptide
tegqpyqpqpa |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 586-718 | 133 | 24 | 1lckA | 83-224 | sh3-sh2 domain fragment
of human p56-lck tyrosine
kinase complexed with
the 10 residue synthetic
phosphotyrosyl peptide
tegqpyqpqpa |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 3-85 | 83 | 100 | 1pht | 3-85 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 6-112 | 107 | 19 | 2kymA | 2-93 | solution structure of
the bem1p sh3-ci domain
from l.elongisporus
in complex with ste20p
peptide |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 614-720 | 107 | 97 | 1h9oA | 2-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 272-428 | 157 | 27 | 2abl | 88-236 | sh3-sh2 domain fragment
of human bcr-abl tyrosine
kinase |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 321-431 | 111 | 97 | 1fu5A | 1-111 | nmr structure of the
n-sh2 domain of the
p85 subunit of pi3-kinase
complexed to a doubly
phosphorylated peptide
derived from polyomavirus
middle t antigen |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 2-57 | 56 | 34 | 2creA | 4-47 | solution structure of
rsgi ruh-036, an sh3
domain from human cdna |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 2-82 | 81 | 100 | 3i5rA | 2-82 | pi3k sh3 domain in complex
with a peptide ligand |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 329-706 | 378 | 14 | 2shpA | 2-426 | tyrosine phosphatase
shp-2 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 3-85 | 83 | 100 | 1pht | 3-85 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 1-111 | 111 | 19 | 1ng2A | 224-319 | structure of autoinhibited
p47phox |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 552-717 | 166 | 24 | 1k9aA | 7-170 | crystal structure analysis
of full-length carboxyl-terminal
src kinase at 2.5 a
resolution |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 2-91 | 90 | 19 | 1i1jB | 18-101 | structure of melanoma
inhibitory activity
protein: a member of
a new family of secreted
proteins |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 613-720 | 108 | 96 | 1h9oA | 1-108 | phosphatidylinositol
3-kinase, p85-alpha
subunit: c-terminal
sh2 domain complexed
with a tyr751 phosphopeptide
from the pdgf receptor,
crystal structure
at 1.79 a |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 329-563 | 235 | 16 | 2shpA | 2-246 | tyrosine phosphatase
shp-2 |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 109-302 | 194 | 23 | 1xa6A | 268-463 | crystal structure of
the human beta2-chimaerin |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 2-295 | 294 | 20 | 2qv2A | 49-334 | a role of the lowe syndrome
protein ocrl in early
steps of the endocytic
pathway |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 555-724 | 170 | 21 | 1fmk | 82-251 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 327-718 | 392 | 25 | 2oq1A | 6-256 | tandem sh2 domains of
zap-70 with 19-mer zeta1
peptide |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 108-302 | 195 | 23 | 1xa6A | 270-463 | crystal structure of
the human beta2-chimaerin |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 327-718 | 392 | 25 | 2oq1A | 6-256 | tandem sh2 domains of
zap-70 with 19-mer zeta1
peptide |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 556-720 | 165 | 24 | 1lckA | 63-226 | sh3-sh2 domain fragment
of human p56-lck tyrosine
kinase complexed with
the 10 residue synthetic
phosphotyrosyl peptide
tegqpyqpqpa |
 | | P27986.2 | p85a_human recname: full=phosphatidylinositol
3-kinase regulatory subunit
alpha; short=pi3-kinase
regulatory subunit alpha;
short=pi3k regulatory subunit
alpha; short=ptdins-3-kinase
regulatory subuni | Homo sapiens | 724 | 115-309 | 195 | 100 | 1pbwB | 115-309 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 3-85 | 83 | 100 | 1pht | 3-85 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 3-85 | 83 | 100 | 1pht | 3-85 | phosphatidylinositol
3-kinase p85-alpha subunit
sh3 domain, residues
1-85 |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 115-298 | 184 | 100 | 1pbwA | 115-298 | structure of bcr-homology
(bh) domain |
 | | P27986 | phosphatidylinositol 3-kinase
regulatory alpha subunit
(pi3-kinasede p85-alpha
subunit) (ptdins-3-kinase
p85-alpha) (pi3k) | Homo sapiens | 724 | 614-724 | 111 | 100 | 1bfi | 1-111 | solution structure of
the c-terminal sh2 domain
of the p85alpha regulatory
subunit of phosphoinositide
3-kinase, nmr, 30 structures |
