| |
| TARGET | MODEL DATA | TEMPLATE |
|---|
Model
Icon | Model/Fold
Reliability | Sequence
Database
Link | Database Annotation | Organism | Protein
Size | Modeled
Segment | Size | Seq
Id(%) | PDB
code | PDB
Segment | PDB Comment |
|---|
 |  | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 544-659 | 116 | 24 | 1nrvA | 429-533 | crystal structure of
the sh2 domain of grb10 |
 |  | 410562818 | a chain a, structure of tandem
sh2 domains from plcgamma1 | | 246 | 121-208 | 88 | 30 | 1jyrA | 57-146 | xray structure of grb2
sh2 domain complexed
with a phosphorylated
peptide |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 548-845 | 298 | 19 | 2shpA | 4-332 | tyrosine phosphatase
shp-2 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 27-142 | 116 | 20 | 1mai | 20-130 | structure of the pleckstrin
homology domain from
phospholipase c delta
in complex with inositol
trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 650-755 | 106 | 28 | 2knoA | 4-128 | nmr solution structure
of sh2 domain of the
human tensin like c1
domain containing phosphatase
(tenc1) |
 | | B7ZLY7 | subname: full=phospholipase
c, gamma 1; | Gorilla gorilla gorilla,
Homo sapiens | 1291 | 952-1207 | 256 | 41 | 3ohmB | 589-840 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 27-142 | 116 | 20 | 1mai | 20-130 | structure of the pleckstrin
homology domain from
phospholipase c delta
in complex with inositol
trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 212-466 | 255 | 44 | 1djxA | 200-442 | phosphoinositide-specific
phospholipase c-delta1
from rat complexed with
inositol-1,4,5-trisphosphate |
 | | B7ZLY7 | subname: full=phospholipase
c, gamma 1; | Gorilla gorilla gorilla,
Homo sapiens | 1291 | 347-384 | 38 | 34 | 1zccA | 16-53 | crystal structure of
glycerophosphodiester
phosphodiesterase from
agrobacterium tumefaciens
str.c58 |
 |  | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 484-937 | 454 | 13 | 1fmk | 83-520 | crystal structure of
human tyrosine-protein
kinase c-src |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 785-967 | 183 | 10 | 1vyvA | 85-340 | beta4 subunit of ca2+
channel |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 788-869 | 82 | 18 | 1i1jB | 16-105 | structure of melanoma
inhibitory activity
protein: a member of
a new family of secreted
proteins |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 667-747 | 81 | 35 | 2ciaA | 284-365 | human nck2 sh2-domain
in complex with a decaphosphopeptide
from translocated intimin
receptor (tir) of epec |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 301-474 | 174 | 51 | 3qr1A | 305-490 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 310-560 | 251 | 16 | 2plc | 26-275 | phosphatidylinositol-specific
phospholipase c from
listeria monocytogenes |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 304-525 | 222 | 13 | 2ptd | 2-244 | phosphatidylinositol-specific
phospholipase c mutant
d198e |
 | | 410562872 | a chain a, insights into
structural integration of
the plcgamma regulatory regio
n and mechanism of autoinhibition
and activation based on key
roles of sh2 domains | | 246 | 3-245 | 243 | 100 | 4fbnA | 547-789 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 1080-1217 | 138 | 17 | 1wfjA | 2-134 | c2 domain-containing
protein from putative
elicitor-responsive
gene |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 547-789 | 243 | 100 | 4fbnA | 547-789 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 663-759 | 97 | 100 | 2fciA | 6-102 | structural basis for
the requirement of two
phosphotyrosines in
signaling mediated by
syk tyrosine kinase |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 148-221 | 74 | 12 | 2pq3A | 3-76 | n-terminal calmodulin
zn-trapped intermediate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 32-1236 | 1205 | 30 | 3qr0A | 25-809 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 170-555 | 386 | 32 | 1djxB | 158-569 | phosphoinositide-specific
phospholipase c-delta1
from rat complexed with
inositol-1,4,5-trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 791-849 | 59 | 95 | 1y0mA | 791-849 | crystal structure of
of the sh3 domain of
phospholipase c gamma-1 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 1073-1276 | 204 | 17 | 1dqvA | 297-508 | crystal structure of
synaptotagmin iii c2a/c2b |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 212-611 | 400 | 31 | 1djxA | 200-634 | phosphoinositide-specific
phospholipase c-delta1
from rat complexed with
inositol-1,4,5-trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 498-637 | 140 | 29 | 1g83A | 98-229 | crystal structure of
fyn sh3-sh2 |
 | | 159162434 | a chain a, solution structure
of the sh3 domain of phospholipase
cgamma | Homo sapiens | 71 | 10-60 | 51 | 38 | 2yuoA | 11-60 | solution structure of
the sh3 domain of mouse
run and tbc1 domain
containing 3 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 537-659 | 123 | 29 | 1mw4A | 6-117 | solution structure of
the human grb7-sh2 domain
in complex with a 10
amino acid peptide py1139 |
 | | B7ZLY7 | subname: full=phospholipase
c, gamma 1; | Gorilla gorilla gorilla,
Homo sapiens | 1291 | 301-474 | 174 | 51 | 3qr1A | 305-490 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 699-1212 | 514 | 20 | 1djxA | 236-755 | phosphoinositide-specific
phospholipase c-delta1
from rat complexed with
inositol-1,4,5-trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 1090-1194 | 105 | 24 | 1rsy | 158-264 | structure of the first
c2-domain of synaptotagmin
i: a novel ca2+(slash)phospholipid
binding fold |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 645-849 | 205 | 26 | 1griA | 37-213 | grb2 |
 | | B7ZLY7 | subname: full=phospholipase
c, gamma 1; | Gorilla gorilla gorilla,
Homo sapiens | 1291 | 489-933 | 445 | 93 | 2fjlA | 1-150 | solution structure of
the split ph domain
in phospholipase c-gamma1 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 655-762 | 108 | 25 | 1csyA | 2-112 | syk tyrosine kinase
c-terminal sh2 domain
complexed with a phosphopeptidefrom
the gamma chain of the
high affinity immunoglobin
g receptor, nmr |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 1090-1194 | 105 | 20 | 3fdwA | 373-482 | crystal structure of
a c2 domain from human
synaptotagmin-like protein
4 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 539-756 | 218 | 25 | 1m61A | 902-254 | crystal structure of
the apo sh2 domains
of zap-70 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 789-849 | 61 | 28 | 1pwt | 1-60 | thermodynamic analysis
of alpha-spectrin sh3
and two of its circular
permutants with different
loop lengths: discerning
the reasons for rapid
folding in proteins |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 798-846 | 49 | 41 | 4hvuA | 88-137 | |
 | | 410562818 | a chain a, structure of tandem
sh2 domains from plcgamma1 | | 246 | 3-245 | 243 | 99 | 4fbnA | 547-789 | |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 212-466 | 255 | 44 | 1djxA | 200-442 | phosphoinositide-specific
phospholipase c-delta1
from rat complexed with
inositol-1,4,5-trisphosphate |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 153-217 | 65 | 18 | 1fw4A | 81-145 | crystal structure of
e. coli fragment tr2c
from calmodulin to 1.7
a resolution |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 1089-1261 | 173 | 20 | 1cjyB | 1019-1182 | human cytosolic phospholipase
a2 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 922-1213 | 292 | 35 | 2fjuB | 459-799 | activated rac1 bound
to its effector phospholipase
c beta 2 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 610-755 | 146 | 24 | 2abl | 88-235 | sh3-sh2 domain fragment
of human bcr-abl tyrosine
kinase |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 636-808 | 173 | 25 | 1opkA | 114-301 | structural basis for
the auto-inhibition
of c-abl tyrosine kinase |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 498-656 | 159 | 32 | 1g83A | 98-245 | crystal structure of
fyn sh3-sh2 |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 663-759 | 97 | 100 | 2pldA | 6-102 | nuclear magnetic resonance
structure of an sh2
domain of phospholipase
c-gamma1 complexed with
a high affinity binding
peptide |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 306-581 | 276 | 14 | 1ptd | 6-267 | phosphatidylinositol-specific
phospholipase c |
 | | P19174 | recname: full=1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase
gamma-1; ec=3.1.4.11;altname:
full=plc-148;altname: full=phosphoinositide
phospholipase c-gamma-1;altname:
full=phospholipase c-i | Homo sapiens | 1290 | 790-858 | 69 | 91 | 1hsq | 3-71 | solution structure of
the sh3 domain of phospholipase
cgamma |
