dbsnp_id nsvar residue_number database_id ligand_code ligand_name pdb_seqident bs_seqident pdb_code pdb_chain model_score model_id description rs13306091 MT 828 P12821 CL 100 100 1uze A 1.00 97e210f1019340c12978211f7474faee near ligand and destabilizing rs629849 GR 1619 P11717 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 100 100 1gp0 A 1.00 822bff0b4be262b5f470fa79dffe2417 near ligand and buried charge rs1042008 HY 149 P50225 NPO P-NITROPHENOL 100 100 1ls6 A 1.00 fee9945f708218c7e37dbb6a07570427 near ligand and buried charge rs2234951 PS 109 P09210 GTX S-HEXYLGLUTATHIONE 95 90.91 1k3y A 1.00 d16c993cce52dcfa618753f3ec37b56d near ligand and helix rs1131215 DY 98 P30460 TYR TYROSINE 94 78.85 1xr9 A 1.00 0a298495aa79b4ba968bd7dd3159589e near ligand and buried charge rs1050696 YH 74 P30460 ILE ISOLEUCINE 94 78.85 1xr9 A 1.00 0a298495aa79b4ba968bd7dd3159589e near ligand and buried charge rs1050696 YH 195 P30460 ILE ISOLEUCINE 94 78.85 1xr9 A 1.00 0a298495aa79b4ba968bd7dd3159589e near ligand and buried charge rs1131215 DY 98 P01889 TYR TYROSINE 93 78.85 1xr9 A 1.00 c1a1194b637ce2e3446de7c772faf079 near ligand and buried charge rs1050696 YH 195 P01889 ILE ISOLEUCINE 93 78.85 1xr9 A 1.00 c1a1194b637ce2e3446de7c772faf079 near ligand and buried charge rs1050696 YH 74 P01889 ILE ISOLEUCINE 93 78.85 1xr9 A 1.00 c1a1194b637ce2e3446de7c772faf079 near ligand and buried charge rs17860364 QR 243 Q9UNI1 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 89 85 1gvk B 1.00 d00ccaf005b2a5f06596fccd151de759 near ligand and buried charge rs1059463 HQ 94 P04439 PRO PROLINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs12721692 DNH 95 P04439 TYR TYROSINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs1059463 HQ 91 P04439 PRO PROLINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs12721692 HDN 95 P04439 TYR TYROSINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs16896018 QL 180 P04439 PRO PROLINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs12721692 DNH 98 P04439 TYR TYROSINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs1059463 QH 94 P04439 PRO PROLINE 88 71.15 1xr9 A 1.00 55c2de79f79589d37b1c290ddc71188b near ligand and buried charge rs1059463 HQ 91 P18462 PRO PROLINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs1059463 HQ 94 P18462 PRO PROLINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs1059463 QH 94 P18462 PRO PROLINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs16896018 QL 180 P18462 PRO PROLINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs12721692 DNH 95 P18462 TYR TYROSINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs12721692 DNH 98 P18462 TYR TYROSINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs12721692 HDN 95 P18462 TYR TYROSINE 87 71.15 1xr9 A 1.00 ad3a20449faa742e9e33427e7c437027 near ligand and buried charge rs2066702 RC 369 P00325 NAJ NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) 87 92.16 1n8k A 1.00 a1166efed415ad3ac77904eb917bc71a near ligand and buried charge rs2066702 RC 369 P00325 ZN 87 92.16 1n8k A 1.00 a1166efed415ad3ac77904eb917bc71a near ligand and buried charge rs1832269 RG 402 P04746 EGL ETHYLENE GLYCOL 87 86.13 1hx0 A 1.00 bdbf5afb36a726e2df11b1b42b89f1a0 near ligand and buried charge rs3200156 DN 98 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs12721692 DNH 95 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs12721692 DNH 98 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs1059463 QH 94 P05534 PRO PROLINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs1059463 HQ 94 P05534 PRO PROLINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs16896018 QL 180 P05534 PRO PROLINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs3200156 ND 101 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs1059463 HQ 91 P05534 PRO PROLINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs12721692 HDN 95 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs3200156 DN 101 P05534 TYR TYROSINE 86 67.31 1xr9 A 1.00 6cf4e11270c86776f15e5d6978462c17 near ligand and buried charge rs12721692 DNH 98 O78126 TYR TYROSINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs1059463 QH 94 O78126 PRO PROLINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs1633399 IT 1394 P53675 MSE SELENOMETHIONINE 85 91.25 1b89 A 1.00 1b000371994788bea84d62a46490527f near ligand and destabilizing rs12721692 HDN 95 O78126 TYR TYROSINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs12721692 DNH 95 O78126 TYR TYROSINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs16896018 QL 180 O78126 PRO PROLINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs1059463 HQ 91 O78126 PRO PROLINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs1059463 HQ 94 O78126 PRO PROLINE 85 69.23 1xr9 A 1.00 8922c3a14dbd346e7dc49f7b195af6fa near ligand and buried charge rs10899862 LS 227 Q6ZN98 GOL GLYCERCOL 82 82.76 1vyb A 1.00 a4c010c4dc425a128320a40c70cc937a near ligand and destabilizing rs1633399 IT 1394 P53675-2 MSE SELENOMETHIONINE 82 91.25 1b89 A 1.00 56d348e73652f2c88371cca53a6e9779 near ligand and destabilizing rs11574936 IN 194 P01375 TRS TRIS(HYDROXYMETHYL)-AMINOMETHANE 81 100 2tnf A 1.00 9408378830ca94683b036df0cd426407 near ligand and destabilizing rs4820853 IT 103 Q9UDX4 VTQ RRR-ALPHA-TOCOPHERYLQUINONE 77 55.17 1olm A 1.00 a410f81d960455b80d94053f2c067533 near ligand and destabilizing rs7580926 QK 122 Q9H853 GTP GUANOSINE TRIPHOSPHATE 75 80 1sa0 A 1.00 e1f3ca56480b5bd1b4e439c43acc6d49 near ligand and buried charge rs9606739 RG 70 Q9UDX3 VTQ RRR-ALPHA-TOCOPHERYLQUINONE 71 55.17 1olm A 1.00 8d0d69d169353aa8f29bfb6ee4ba4bab near ligand and buried charge rs9606739 RG 124 Q9UDX3 VTQ RRR-ALPHA-TOCOPHERYLQUINONE 71 55.17 1olm A 1.00 8d0d69d169353aa8f29bfb6ee4ba4bab near ligand and buried charge rs9606739 RG 70 Q6ICM2 VTQ RRR-ALPHA-TOCOPHERYLQUINONE 69 55.17 1olm A 1.00 30eab7ef79f2336b2339200fafec54e0 near ligand and buried charge rs9606739 RG 124 Q6ICM2 VTQ RRR-ALPHA-TOCOPHERYLQUINONE 69 55.17 1olm A 1.00 30eab7ef79f2336b2339200fafec54e0 near ligand and buried charge rs17632542 IT 179 Q8IXI4 ACT ACETATO GROUP 59 50 1gvz A 1.00 20ca221019e1aeeb8b924a81acc17565 near ligand and destabilizing rs17632542 IT 138 Q8IXI4 ACT ACETATO GROUP 59 50 1gvz A 1.00 20ca221019e1aeeb8b924a81acc17565 near ligand and destabilizing rs2053724 PA 333 Q8N608 NAG N-ACETYLGLUCOSAMINE 52 36.11 1xfd A 1.00 2326856f13c09b6f84de5273c707c17c near ligand and destabilizing rs1799807 DG 98 P06276 GMN TRIETHYLETHANAMINIUM] 52 41.46 1n5m A 1.00 2252faa2ebed474fa82efbd62a9e53a6 near ligand and buried charge rs2053724 AP 340 Q8N608 NAG N-ACETYLGLUCOSAMINE 52 36.11 1xfd A 1.00 2326856f13c09b6f84de5273c707c17c near ligand and destabilizing rs9534899 AP 81 Q9P2R7 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 47 73.68 2scu B 1.00 f51717ddf42d181ce64260994fb4835b near ligand and destabilizing rs9534899 AP 103 Q9P2R7 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 47 73.68 2scu B 1.00 f51717ddf42d181ce64260994fb4835b near ligand and destabilizing rs9534899 AP 103 Q9P2R7-2 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 47 73.68 2scu B 1.00 56a5032fff37fe072232c0edb0ccf3fd near ligand and destabilizing rs9534899 AP 81 Q9P2R7-2 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 47 73.68 2scu B 1.00 56a5032fff37fe072232c0edb0ccf3fd near ligand and destabilizing rs2286622 KM 196 Q9UBS0 THR THREONINE 46 63.46 1o6l A 1.00 302659e0808111fd076228d82cab5f08 near ligand and buried charge rs2286622 KM 196 Q9UBS0 ANP 5'-ADENYL-IMIDO-TRIPHOSPHATE 46 63.46 1o6l A 1.00 302659e0808111fd076228d82cab5f08 near ligand and buried charge rs2228259 CS 246 P52630 AU 46 60.87 1yvl A 1.00 084eca0a2e956f1489a244349a525d99 near ligand and destabilizing rs2286622 KM 196 Q9UBS0 MN 46 63.46 1o6l A 1.00 302659e0808111fd076228d82cab5f08 near ligand and buried charge rs310680 CY 147 P30679 MSE SELENOMETHIONINE 45 46.88 1got A 1.00 5875b5ee4f0767b1b19712ca56efe69b near ligand and destabilizing rs3829078 QR 326 Q16790 NAG N-ACETYLGLUCOSAMINE 44 66.67 1rj5 A 1.00 870ed24b9c0e9e51c1abfe1d2369605d near ligand and buried charge rs1130183 RHCY 271 P78508 MSE SELENOMETHIONINE 44 54.24 1n9p A 1.00 57c59aa94c20d1187740c1dd71a94d68 near ligand and desolubilizing rs3795339 RHCY 271 P78508 MSE SELENOMETHIONINE 44 54.24 1n9p A 1.00 57c59aa94c20d1187740c1dd71a94d68 near ligand and desolubilizing rs17091187 AS 180 P04001 ZN 43 41.07 1u19 A 1.00 8782ff8d9e91c1cc346c371bfb5ab4dc near ligand and destabilizing rs17341257 FY 309 P04001 RET RETINAL 43 41.07 1u19 A 1.00 8782ff8d9e91c1cc346c371bfb5ab4dc near ligand and destabilizing rs17091187 SA 180 P04001 ZN 43 41.07 1u19 A 1.00 8782ff8d9e91c1cc346c371bfb5ab4dc near ligand and destabilizing rs1065441 FY 309 P04001 RET RETINAL 43 41.07 1u19 A 1.00 8782ff8d9e91c1cc346c371bfb5ab4dc near ligand and destabilizing rs12721529 YH 329 Q03113 MSE SELENOMETHIONINE 42 43.75 1got A 1.00 5056be8d6d7fb7d3a5d522d50ec7fed9 near ligand and buried charge rs12721529 YH 182 Q03113 MSE SELENOMETHIONINE 42 43.75 1got A 1.00 5056be8d6d7fb7d3a5d522d50ec7fed9 near ligand and buried charge rs7080536 GE 534 Q14520 TYR TYROSINE 40 60 1gct A 1.00 b21e6ff196a7416ab8f82a00ec3d3588 near ligand and buried charge rs1042008 HY 149 P50225 NA 37 51.11 1q20 A 1.00 9620c775e831f6d8a7998a3e9b296bf8 near ligand and buried charge rs4275364 HP 132 Q9UK32 MPD 2-METHYL-2,4-PENTANEDIOL 37 52.73 1rdq E 1.00 df178ed2976ef4774cea2f37f4bafded near ligand and buried charge rs7580926 QK 122 Q9H853 GDP GUANOSINE DIPHOSPHATE 36 57.58 1sa0 B 1.00 df5edc0a9ec08ff0bf292699d8146199 near ligand and buried charge rs11076126 EK 155 Q6NT32 GOL GLYCERCOL 34 24.29 1p0i A 1.00 bfa5caf1c8fc777cf477888b7e17a281 near ligand and buried charge rs11076126 EK 261 Q6NT32 GOL GLYCERCOL 34 24.29 1p0i A 1.00 bfa5caf1c8fc777cf477888b7e17a281 near ligand and buried charge rs3127785 DE 309 Q9BQS2 MG 33 21.43 1dqv A 1.00 9aaecfd077c0ce7e909329fb7a006399 near ligand and destabilizing rs9527025 CS 370 Q5VZ95 BGC BETA-D-GLUCOSE 33 41.18 1h49 A 1.00 8bd05726d084f9244dfb9c6d396b604d near ligand and destabilizing rs3127785 DE 362 Q9BQS2-3 MG 33 21.43 1dqv A 1.00 9f7d7863bd446e41df7a8b41f1adccef near ligand and destabilizing rs3127785 DE 309 Q9BQS2-3 MG 33 21.43 1dqv A 1.00 9f7d7863bd446e41df7a8b41f1adccef near ligand and destabilizing rs3127785 DE 362 Q9BQS2 MG 33 21.43 1dqv A 1.00 9aaecfd077c0ce7e909329fb7a006399 near ligand and destabilizing rs3127785 ED 188 Q9BQS2 MG 33 21.43 1dqv A 1.00 9aaecfd077c0ce7e909329fb7a006399 near ligand and destabilizing rs1689965 CR 142 Q6ZNC6 CO 31 61.29 2gli A 0.89 e8fc8d4c05847a8aa0e17826584be4a4 near ligand and buried charge rs17610395 AT 275 P50416 MSE SELENOMETHIONINE 31 28.57 1ndb A 1.00 ff217b44d2d78a1a865f5d8b5e0a50bb near ligand and destabilizing rs11258565 QH 258 Q9P2Q2 MSE SELENOMETHIONINE 30 35.94 1ef1 A 1.00 513aa9f00aad08b4d039c5ada19c3b9c near ligand and buried charge rs17052017 SN 456 P13196 MSE SELENOMETHIONINE 30 36.54 1fc4 A 1.00 4b7493f53baccdc3c721a103fe7109d3 near ligand and destabilizing rs11258565 QH 227 Q9P2Q2 MSE SELENOMETHIONINE 30 35.94 1ef1 A 1.00 513aa9f00aad08b4d039c5ada19c3b9c near ligand and buried charge rs1139776 VE 848 P35968 P16 PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE 29 43.75 1opk A 1.00 71512024d55aec7be10c89477da5233f near ligand and buried charge rs2291343 SN 576 Q8IY78 NAG N-ACETYLGLUCOSAMINE 29 43.75 1l3w A 1.00 4650af2b7858c2d497e955f30343c8c4 near ligand and destabilizing rs2291343 SN 576 Q9ULB5 NAG N-ACETYLGLUCOSAMINE 29 43.75 1l3w A 1.00 de6bbe64b476a7211871b94a661adb2e near ligand and destabilizing rs1657535 SI 86 Q8WXQ0 EDO ETHANEDIOL 28 22.22 1oll A 1.00 4ea84ccf9bf82076dc27c96e13599d75 near ligand and destabilizing rs1657535 IS 101 Q8WXQ0 EDO ETHANEDIOL 28 22.22 1oll A 1.00 4ea84ccf9bf82076dc27c96e13599d75 near ligand and destabilizing rs1657535 IS 101 Q8WXQ1 EDO ETHANEDIOL 28 22.22 1oll A 1.00 7ebce84a12027f717b46c0e508312444 near ligand and destabilizing rs1657535 SI 97 Q8WXQ1 EDO ETHANEDIOL 28 22.22 1oll A 1.00 7ebce84a12027f717b46c0e508312444 near ligand and destabilizing rs1657535 IS 86 Q8WXQ0 EDO ETHANEDIOL 28 22.22 1oll A 1.00 4ea84ccf9bf82076dc27c96e13599d75 near ligand and destabilizing rs1657535 IS 86 Q8WXQ1 EDO ETHANEDIOL 28 22.22 1oll A 1.00 7ebce84a12027f717b46c0e508312444 near ligand and destabilizing rs1657535 IS 97 Q8WXQ1 EDO ETHANEDIOL 28 22.22 1oll A 1.00 7ebce84a12027f717b46c0e508312444 near ligand and destabilizing rs1657535 IS 97 Q8WXQ0 EDO ETHANEDIOL 28 22.22 1oll A 1.00 4ea84ccf9bf82076dc27c96e13599d75 near ligand and destabilizing rs1657535 SI 97 Q8WXQ0 EDO ETHANEDIOL 28 22.22 1oll A 1.00 4ea84ccf9bf82076dc27c96e13599d75 near ligand and destabilizing rs6114 GR 217 P05154 MPD 2-METHYL-2,4-PENTANEDIOL 28 28.57 1tb6 I 1.00 a74daba3b02046d5c5e25c037d101a6c near ligand and buried charge rs17580 EV 288 P01009 MPD 2-METHYL-2,4-PENTANEDIOL 28 24.69 1tb6 I 1.00 b2510110a7feca328a98651757261658 near ligand and buried charge rs1657535 SI 86 Q8WXQ1 EDO ETHANEDIOL 28 22.22 1oll A 1.00 7ebce84a12027f717b46c0e508312444 near ligand and destabilizing rs2143598 EA 52 O95258 CXT CARBOXYATRACTYLOSIDE 27 27.71 1okc A 0.07 f8145da108089132700972dff32fd234 near ligand and buried charge rs2143598 EA 52 O95258-2 CXT CARBOXYATRACTYLOSIDE 27 27.71 1okc A 0.10 0b270d43f283a06f2c1762e5acec6e65 near ligand and buried charge rs2143598 EA 55 O95258-2 CXT CARBOXYATRACTYLOSIDE 27 27.71 1okc A 0.10 0b270d43f283a06f2c1762e5acec6e65 near ligand and buried charge rs1060877 CS 310 Q9UIE0 CO 27 58.62 2gli A 0.99 d87bf6aa4ea6d65745f5d6ef812538ca near ligand and destabilizing rs2143598 EA 55 O95258 CXT CARBOXYATRACTYLOSIDE 27 27.71 1okc A 0.07 f8145da108089132700972dff32fd234 near ligand and buried charge rs3745775 RQ 301 Q6PG37 ZN 26 48.57 1tf6 A 0.15 0eea247e16007b7d4e7c95a575328ca8 near ligand and buried charge rs1830035 YH 212 Q8IYX0 ZN 26 48.48 1tf6 A 0.17 1581792599c92b43a2820d952f9a05fc near ligand and buried charge rs187316 LP 1622 Q96L96 ANP 5'-ADENYL-IMIDO-TRIPHOSPHATE 25 66.67 1ia9 A 0.79 59cfac4ac066dc3782d7c1131e7ff631 near ligand and destabilizing rs1060877 CS 310 Q9UIE0 ZN 25 45.71 1tf6 A 0.35 97c433dccd7456828ed0de9a146114c9 near ligand and destabilizing rs8109165 YH 196 Q96P09 ZN 25 52.94 1jm7 A 0.79 38afae90a6581475e1f925cdfa3e3fc8 near ligand and buried charge rs6475 IN 172 P08686 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 25 58.62 1po5 A 1.00 703c2ddc0999c93b4612cd773521fc5b near ligand and destabilizing rs11569892 CY 273 P28908 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 25 35.71 1jma B 0.65 5e5dca3426f4155e447487bfb4c11efe near ligand and destabilizing rs1059199 EK 260 Q6V9R5 ZN 24 48.48 1tf6 A 0.53 9e97f92a57eefc01c7f8a4c8dd8ddaca near ligand and buried charge rs3740772 RC 208 Q8WUA8 NAG N-ACETYLGLUCOSAMINE 24 8.57 1ziw A 1.00 d0f881d717f305a91ead70302fadaa76 near ligand and desolubilizing rs12608979 AT 93 Q8NBN7 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 24 35.71 1wma A 1.00 8dfedf0abd24c6d6ff252450224b3809 near ligand and destabilizing rs3177338 RC 425 Q96C13 GNP SEE REMARK 5 23 43.48 1vg8 A 0.46 5e131767692d88146e6337e4453b3ce2 near ligand and desolubilizing rs7080536 GE 534 Q14520 ARM L-ARGININAMIDE 23 60 1z8g A 1.00 8df5c5fc1bf5d7f4db176b3334f457dd near ligand and buried charge rs1059199 EK 188 Q9NXS5 ZN 23 45.45 1tf6 A 0.34 1f21670e494b1eb27b167b73cab66471 near ligand and buried charge rs5880 AP 330 P11597 PC2 DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE 23 25 1ewf A 1.00 b113fd5fb888fb8255cdab75f1d44a59 near ligand and destabilizing rs11604671 GR 318 Q8NFD2 FMM QUINAZOLINAMINE 23 42.86 1xkk A 1.00 96c814c6c670d3bdd15bdc4dae3ca22d near ligand and buried charge rs5880 AP 390 P11597 PC2 DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE 23 25 1ewf A 1.00 b113fd5fb888fb8255cdab75f1d44a59 near ligand and destabilizing rs1059199 EK 260 Q9NXS5 ZN 23 45.45 1tf6 A 0.34 1f21670e494b1eb27b167b73cab66471 near ligand and buried charge rs2227843 SN 233 P21918 ZN 22 22.64 1u19 A 0.10 62daab9a414ff7a80fd351dca60b8192 near ligand and destabilizing rs7882107 ND 130 Q5JSL5 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 ae09400bff689bca67eafe097d1f96aa near ligand and buried charge rs7882107 ND 130 Q5JSL7 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 9dc5b2907fa6e37c64c4d5ed5ebfc4af near ligand and buried charge rs4986891 RQ 128 P11509 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 22 40 1tqn A 1.00 b65c762d9a512b71c1764e575b44432a near ligand and buried charge rs3776099 AT 421 Q9Y5E5 NAG N-ACETYLGLUCOSAMINE 22 38.4 1l3w A 1.00 c048774edc3c676fb4017f60c8704c96 near ligand and destabilizing rs2907306 HR 483 Q96TA0 NAG N-ACETYLGLUCOSAMINE 22 37.01 1l3w A 1.00 09cd8751ec1a8640d0589018b586f199 near ligand and destabilizing rs7882107 ND 202 Q5JSL5 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 ae09400bff689bca67eafe097d1f96aa near ligand and buried charge rs7882107 ND 202 O43307 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 1a1f10e09d1df810b66c7a701ad8e8ee near ligand and buried charge rs2227843 SN 233 P21918 RET RETINAL 22 22.64 1u19 A 0.10 62daab9a414ff7a80fd351dca60b8192 near ligand and destabilizing rs7882107 ND 202 Q5JSL7 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 9dc5b2907fa6e37c64c4d5ed5ebfc4af near ligand and buried charge rs13383830 ND 288 Q9UJ71 CA 22 28.57 1rtm 1 1.00 9d38e4b9bd25bcc44eaeabd516b55ee7 near ligand and buried charge rs2128600 QH 169 P54577 TYB TYROSINAL 22 29.63 1h3f A 0.84 724ea0aad35af0ccdb2c3fd77cb2fa0a near ligand and buried charge rs4871827 SN 360 Q9H0R7 PHE PHENYLALANINE 22 16.67 1ihj A 0.28 48569936ca0064bbba0643e5e9f0b446 near ligand and destabilizing rs450046 QR 437 O43272 1PE PENTAETHYLENE GLYCOL 22 37.31 1k87 A 1.00 51536facd41208408fbbdd63b9aaa8a1 near ligand and buried charge rs7882107 ND 149 Q5JSL7 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 9dc5b2907fa6e37c64c4d5ed5ebfc4af near ligand and buried charge rs4871827 SN 389 Q9H0R7 PHE PHENYLALANINE 22 16.67 1ihj A 0.28 48569936ca0064bbba0643e5e9f0b446 near ligand and destabilizing rs7882107 ND 149 Q5JSL5 MSE SELENOMETHIONINE 22 36.49 1foe A 1.00 ae09400bff689bca67eafe097d1f96aa near ligand and buried charge rs3733920 SR 99 Q99467 GOL GLYCERCOL 21 11.27 1ziw A 1.00 83a3296215d4891fa2119816067c35a6 near ligand and buried charge rs2230520 SR 99 Q99467 GOL GLYCERCOL 21 11.27 1ziw A 1.00 83a3296215d4891fa2119816067c35a6 near ligand and buried charge rs3744900 SN 120 Q9NWM7 PLP PYRIDOXAL 5(PRIME)-PHOSPHATE 21 56.25 1jf9 A 1.00 d65dcd2583ea2f374d1b82260c45fae4 near ligand and destabilizing rs28745274 FY 68 Q99518 MSE SELENOMETHIONINE 21 31.17 1vqw A 0.85 4f24c9ff1262874834f32f255cf2d8aa near ligand and destabilizing rs17880696 RC 311 P49019 PLY PALMITOYL 20 21.5 1u19 A 0.11 1113a7551b1f98c60c665a3a4449f3b5 near ligand and desolubilizing rs17880696 RC 311 Q8TDS4 PLY PALMITOYL 20 21.5 1u19 A 0.06 6e5d26481c9107df9e1e6a413ab3c2fc near ligand and desolubilizing rs6967330 CY 529 Q6ZTQ4 CA 20 28.57 1l3w A 1.00 7ae5f4f14d877474767dac7dc227d187 near ligand and destabilizing rs7065449 RC 343 O43900 ZN 20 60.61 1b8t A 0.44 f1c0d75451996d24a6dc9ffce72e6293 near ligand and desolubilizing rs1056936 HY 676 P41182 ZN 20 34.29 1tf6 A 0.56 2d1ce5d498c67cd858f318deea2b5236 near ligand and buried charge rs7107481 DG 112 P08173 RET RETINAL 20 16.82 1u19 A 0.02 67df383586c61e343d6496dc6ff3bbcb near ligand and buried charge rs5232 TP 53 P32247 PLY PALMITOYL 20 19.66 1u19 A 0.06 1928e44f981982cba82055dfbfc1e1e5 near ligand and helix rs3735080 RC 83 Q8NHV1 GOL GLYCERCOL 20 37.84 1wf3 A 0.53 215ab72a854de37ace2ad8cbd4476552 near ligand and desolubilizing rs7314976 RC 311 Q8TDS4 PLY PALMITOYL 20 21.5 1u19 A 0.06 6e5d26481c9107df9e1e6a413ab3c2fc near ligand and desolubilizing rs1830035 YH 212 Q8IYX0 MG 20 27.59 1un6 B 0.13 e4bfda0a855ecc05c7afc3642bec5bbc near ligand and buried charge rs703903 QR 125 P47881 HG 19 13.4 1u19 A 0.42 83fb35ec02069edda926b85434b70c60 near ligand and buried charge rs4985162 PL 301 Q6P996 PLP PYRIDOXAL 5(PRIME)-PHOSPHATE 19 12.5 1js3 A 1.00 9d905054611d361829e6d25fa1a4b94b near ligand and helix rs17418077 GD 127 P18577-2 MSE SELENOMETHIONINE 19 14.74 1u7g A 0.74 f7085d6ae62011d5584659de22ad29fc near ligand and buried charge rs17418077 GD 112 P18577-2 MSE SELENOMETHIONINE 19 14.74 1u7g A 0.74 f7085d6ae62011d5584659de22ad29fc near ligand and buried charge rs4985162 PL 301 Q6PID7 PLP PYRIDOXAL 5(PRIME)-PHOSPHATE 19 12.5 1js3 A 1.00 37bbd7aa7f84b7c36e05819fcf785215 near ligand and helix rs1644731 MT 110 Q9H838 DCN DICLOSAN 19 31.58 1jw7 A 0.80 a929d0348ad25bf993c8e8bcabafacc8 near ligand and destabilizing rs1053347 GD 112 P18577-2 MSE SELENOMETHIONINE 19 14.74 1u7g A 0.74 f7085d6ae62011d5584659de22ad29fc near ligand and buried charge rs9305052 QE 183 O76100 RET RETINAL 19 12.5 1u19 A 0.12 85faa8c248e27f29ca1f43d2f69b164d near ligand and buried charge rs2293859 IR 85 Q8IZJ6 ATP BOUND AS AMP-PNP 19 44 1z7e A 0.43 7799d4d3f49f8f23bd982eb13d7481b8 near ligand and buried charge rs2446543 AP 656 P26927 ARM L-ARGININAMIDE 19 36 1z8g A 0.53 d6f4d883788e13dc18b6b692298e5007 near ligand and destabilizing rs1053347 GD 127 P18577-2 MSE SELENOMETHIONINE 19 14.74 1u7g A 0.74 f7085d6ae62011d5584659de22ad29fc near ligand and buried charge rs1644731 MT 110 Q9H838 NAD NICOTINAMIDE-ADENINE DINUCLEOTIDE COFCT 19 31.58 1jw7 A 0.80 a929d0348ad25bf993c8e8bcabafacc8 near ligand and destabilizing rs2229967 AS 99 P50391 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 19 15 1u19 A 0.02 b22bd540d99854f9cc5d8a3b82b025e6 near ligand and destabilizing rs4298923 MT 200 Q96R09 RET RETINAL 19 18.09 1u19 A 0.08 055c5e54a7fc355e85405554a789cb82 near ligand and destabilizing rs3177338 RC 425 Q96C13 GDP GUANOSINE DIPHOSPHATE 19 44.44 1xtq A 0.11 d7b51accec4a4df44abc8bb708679870 near ligand and desolubilizing rs17207364 AT 107 Q7Z5H2 MPD 2-METHYL-2,4-PENTANEDIOL 19 9.52 1sjx A 0.28 3d23983a10e11e818098e5d605c03306 near ligand and destabilizing rs10888267 RC 179 Q7Z3T1 RET RETINAL 19 15.46 1u19 A 0.17 3742451b943f95003c0f00a653dda66b near ligand and buried charge rs5749 AT 160 P21731-2 ZN 19 20.22 1u19 A 0.21 767d08d095ea33e706d6471923444a55 near ligand and destabilizing rs2293859 RI 85 Q8IZJ6 ATP BOUND AS AMP-PNP 19 44 1z7e A 0.43 7799d4d3f49f8f23bd982eb13d7481b8 near ligand and buried charge rs5742906 PL 39 P51677 HTO HEPTANE-1,2,3-TRIOL 19 18.75 1u19 A 0.05 79f921a58d61021e32d40cdec3f5db55 near ligand and helix rs5749 AT 160 O75228 ZN 19 20.22 1u19 A 0.23 dbb0546da63ad19c5275f595b10d3e62 near ligand and destabilizing rs3130743 AT 218 O76002 HG 19 15.15 1u19 A 0.29 a985b8014a8508726be00791540f3b02 near ligand and destabilizing rs8110393 PL 288 Q6ZS11 MSE SELENOMETHIONINE 18 16.42 1txu A 0.81 4bfd550bf00e47653731f110caa2db51 near ligand and helix rs10176036 RC 122 Q8NGW0 HG 18 18.09 1u19 A 0.23 6d1b7e67c3dcc2e7b8fa761511384919 near ligand and buried charge rs4985162 PL 7 Q6XYB5 PLP PYRIDOXAL 5(PRIME)-PHOSPHATE 18 0 1js3 A 0.18 f3a18f79d307a8476bb98a7ee929a9c7 near ligand and helix rs2072164 RC 122 Q13607 HG 18 15.84 1u19 A 0.12 2ab0a3cec4fa1e16abe05353419a0bf1 near ligand and buried charge rs5312 EV 383 P15538 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 18 24 1x8v A 1.00 265bde718bea0a850d3355fcdb245cce near ligand and buried charge rs2513726 CY 173 Q8NGQ2 RET RETINAL 18 13.98 1u19 A 0.06 763386b0b7abc596510d1db517c1f218 near ligand and destabilizing rs2511241 LP 46 P41231 PLY PALMITOYL 18 16.67 1u19 A 0.05 7754bbcbb5eacfc1a4eb40d852fe11a9 near ligand and helix rs5312 EV 99 P15538 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 18 24 1x8v A 1.00 265bde718bea0a850d3355fcdb245cce near ligand and buried charge rs2442426 MT 288 Q8NGJ7 PLY PALMITOYL 18 19 1u19 A 0.11 d08f1f03ac9bf7d275bd3cf32c96d80e near ligand and destabilizing rs2442426 MT 288 Q8NGJ7 HG 18 19 1u19 A 0.11 d08f1f03ac9bf7d275bd3cf32c96d80e near ligand and destabilizing rs1566275 HR 124 Q8NGJ2 HG 18 13.59 1u19 A 0.04 c49d8b9cae6cf31cbad5790727f7e568 near ligand and destabilizing rs5749 AT 160 P21731 ZN 18 20 1u19 A 0.50 51ffac02220062f3e5ec7347ffc7018f near ligand and destabilizing rs6902566 HR 91 O00270 RET RETINAL 17 15.53 1u19 A 0.02 e20cc1a008cd63d90bd9d3f712a567cf near ligand and destabilizing rs2286672 RC 172 O14939-3 GOL GLYCERCOL 17 18.18 1kq6 A 0.80 f97475b36ee5d675f31127b1feb21bc8 near ligand and desolubilizing rs9903671 EQ 103 P47883 RET RETINAL 17 12.94 1u19 A 0.17 f41a79f035edbfc890423d30d7246b3b near ligand and buried charge rs5312 EV 383 P19099 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 17 24 1x8v A 1.00 50917dcada17fdb0773a3991b2e1b597 near ligand and buried charge rs2286672 RC 172 O14939-3 MSE SELENOMETHIONINE 17 18.18 1kq6 A 0.80 f97475b36ee5d675f31127b1feb21bc8 near ligand and desolubilizing rs3745601 AT 87 Q96G91 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 17 15 1u19 A 0.08 570bbfb6fd44d245066ba5f08fe4bec3 near ligand and destabilizing rs10176036 RC 122 Q8NGW1 HG 17 16 1u19 A 0.13 85e318e65d167f55f597698b8d612214 near ligand and buried charge rs5312 EV 99 P19099 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 17 24 1x8v A 1.00 50917dcada17fdb0773a3991b2e1b597 near ligand and buried charge rs4084209 VE 195 Q8NGN3 RET RETINAL 17 15.05 1u19 A 0.02 da2f90d621272fad30d98fca343a219d near ligand and buried charge rs7936512 IT 106 Q8NGI2 RET RETINAL 17 15.15 1u19 A 0.06 f197719e8916191d9cd4fddf3a1a6bd5 near ligand and destabilizing rs7025570 PS 79 Q8NGS8 PLY PALMITOYL 17 16.84 1u19 A 0.03 f53f75d63868cbbd668da92369c8dca2 near ligand and helix rs4075258 LP 82 Q8NH09 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 17 14.29 1u19 A 0.02 476c1005d7ca092d046aee8acbfcc299 near ligand and helix rs499037 RQW 123 Q8NGI7 HG 17 15.22 1u19 A 0.04 575a1ffc3f35405bd0fd17c0f66154bc near ligand and buried charge rs3923647 HL 305 Q15399 NAG N-ACETYLGLUCOSAMINE 17 9.23 1ziw A 0.98 0af43493f7b7218ec9f83bb65ef69b3d near ligand and buried charge rs6464573 AS 136 Q96R48 RET RETINAL 17 12.12 1u19 A 0.02 8aa6584505727aa2fe037252dac7bec9 near ligand and destabilizing rs2073153 LR 120 P58182 HG 17 14.89 1u19 A 0.07 ebf0e3031d8fcb648ef6563ebcc624cb near ligand and buried charge rs2306066 DN 389 Q9HBB8-2 CA 17 23.89 1l3w A 0.84 af56f01cdfc53dc93f1b8d8c4efc5d0f near ligand and buried charge rs11191439 MT 287 Q9HBK9 UNK UNKNOWN ION PROBABLY A POTASSIUM 17 20 1or8 A 0.46 44f1315474141155b78324457c4481ca near ligand and destabilizing rs7025570 PS 79 Q8NGS9 PLY PALMITOYL 17 16.33 1u19 A 0.21 410f555573beed59965c1b32c3536697 near ligand and helix rs499033 RQW 123 Q8NGI7 HG 17 15.22 1u19 A 0.04 575a1ffc3f35405bd0fd17c0f66154bc near ligand and buried charge rs7121276 AS 259 Q8NH87 RET RETINAL 17 17.39 1u19 A 0.06 8ffbc5cfa24b9c46b7e31de65674eacc near ligand and destabilizing rs4936845 TK 276 Q8NGM8 RET RETINAL 17 17.39 1u19 A 0.13 3a1fd72a87fd0da6db02089a49013fe8 near ligand and buried charge rs231678 AS 193 P47883 ZN 17 12.94 1u19 A 0.17 f41a79f035edbfc890423d30d7246b3b near ligand and destabilizing rs2230344 PS 37 P49685 HTO HEPTANE-1,2,3-TRIOL 16 18.42 1u19 A 0.02 d91fd1031b48d54e53b80920a4778620 near ligand and helix rs1966834 HR 122 Q8NH92 HG 16 10 1u19 A 0.04 10114e3e92d76260776f307572bcb578 near ligand and destabilizing rs1053347 GD 127 P18577-3 MSE SELENOMETHIONINE 16 13.56 1u7g A 0.05 43512ea3d5d570c04844d0822c943399 near ligand and buried charge rs2508162 SFC 79 Q8NG94 PLY PALMITOYL 16 14.71 1u19 A 0.14 777a545fb15d617568d6ea4680a9436f near ligand and desolubilizing rs10450603 RC 122 Q9H344 HG 16 16.16 1u19 A 0.08 bed711c14462e798566d0dc07b882dfa near ligand and buried charge rs9853887 CR 179 Q8NGV6 RET RETINAL 16 17.89 1u19 A 0.07 3105eb859915f9037fbb1f4e75cb83e6 near ligand and buried charge rs16987625 MT 83 O75679 ZN 16 47.06 1jm7 A 0.79 b24a708f9896ac7504dd5bf565f3be85 near ligand and destabilizing rs17418077 GD 112 P18577-3 MSE SELENOMETHIONINE 16 13.56 1u7g A 0.05 43512ea3d5d570c04844d0822c943399 near ligand and buried charge rs11032296 RC 124 Q8NGK3 HG 16 13.86 1u19 A 0.08 43e38dc8678e06dd707f20209c9d45f9 near ligand and buried charge rs960193 LR 122 Q8NH51 HG 16 13.68 1u19 A 0.21 3d81a7fb006ce72e0e70943c2b7995bf near ligand and buried charge rs2815979 SP 258 Q8NG94 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 16 14.71 1u19 A 0.14 777a545fb15d617568d6ea4680a9436f near ligand and helix rs2486699 CY 168 O60813 NAG N-ACETYLGLUCOSAMINE 16 13.33 1wwl A 0.06 5c7321eaf635c2180134750ccecd4acb near ligand and destabilizing rs1053347 GD 112 P18577-3 MSE SELENOMETHIONINE 16 13.56 1u7g A 0.05 43512ea3d5d570c04844d0822c943399 near ligand and buried charge rs11229411 AT 181 Q8NH48 RET RETINAL 16 14.89 1u19 A 0.18 a12d4a773761187d80fa183d6f6b97d7 near ligand and destabilizing rs10985760 IT 215 Q8NGR2 HG 16 15.31 1u19 A 0.09 97591db1de43d8de66392742046ea284 near ligand and destabilizing rs17184100 DE 288 P35410 ZN 16 14.61 1u19 A 0.00 79638368d275fc28825a545343538801 near ligand and destabilizing rs17104742 PL 40 Q8TDV0 HTO HEPTANE-1,2,3-TRIOL 16 15.93 1u19 A 0.12 63906392f297b431dcda87a619d81ed0 near ligand and helix rs13235235 YH 278 O95006 RET RETINAL 16 14.74 1u19 A 0.08 4d972fa80d8b6813ef9a9d242f687730 near ligand and buried charge rs17152661 PL 30 Q8NH48 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 16 14.89 1u19 A 0.18 a12d4a773761187d80fa183d6f6b97d7 near ligand and helix rs2657167 SR 305 Q8NGK5 HG 16 14.85 1u19 A 0.03 899a1f5ac88eb67426a2de2949daf364 near ligand and buried charge rs2486699 CY 126 O60813 NAG N-ACETYLGLUCOSAMINE 16 13.33 1wwl A 0.06 5c7321eaf635c2180134750ccecd4acb near ligand and destabilizing rs10838093 CR 153 Q8NH59 ZN 16 15.84 1u19 A 0.05 ba36f12f042a4eac9ce6a0630c546085 near ligand and buried charge rs16840980 GD 56 Q8NGW6 HG 16 15.79 1u19 A 0.21 c10bf13714b5e37dface01c4d8f9b779 near ligand and buried charge rs559449 PL 259 Q8NGL9 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 16 15.46 1u19 A 0.07 44ebeb4866a8d4499557f88badb0bee8 near ligand and helix rs7952293 RC 120 Q9Y5P1 HG 16 13.33 1u19 A 0.01 36d2ad6fbeab77676d1ab9fb79e871d7 near ligand and buried charge rs297055 LP 290 Q8NGL3 HTG HEPTYL 1-THIOHEXOPYRANOSIDE 16 14.29 1u19 A 0.08 7647aefca7d56cf192700f8092041502 near ligand and helix rs17152661 PL 30 Q8NH48 PLY PALMITOYL 16 14.89 1u19 A 0.18 a12d4a773761187d80fa183d6f6b97d7 near ligand and helix rs3738247 DE 288 Q9NR50 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 16 15.38 1yp2 A 0.24 84d1cd946ac6442e84e2ba268a21e24f near ligand and destabilizing rs2486699 CY 166 O60813 NAG N-ACETYLGLUCOSAMINE 16 13.33 1wwl A 0.06 5c7321eaf635c2180134750ccecd4acb near ligand and destabilizing rs2173236 SLW 72 Q8NGV6 PLY PALMITOYL 16 17.89 1u19 A 0.07 3105eb859915f9037fbb1f4e75cb83e6 near ligand and destabilizing rs297055 LP 290 Q8NGL3 PLY PALMITOYL 16 14.29 1u19 A 0.08 7647aefca7d56cf192700f8092041502 near ligand and helix rs17418077 GD 127 P18577-3 MSE SELENOMETHIONINE 16 13.56 1u7g A 0.05 43512ea3d5d570c04844d0822c943399 near ligand and buried charge rs16931292 RP 151 Q9H344 ZN 16 16.16 1u19 A 0.08 bed711c14462e798566d0dc07b882dfa near ligand and buried charge rs9367359 ND 161 Q5SZD3 MSE SELENOMETHIONINE 16 20.93 1sqh A 1.00 5c6a59b0203a59320952a42b1342aed5 near ligand and buried charge rs17152661 PL 30 Q8NH48 HTO HEPTANE-1,2,3-TRIOL 16 14.89 1u19 A 0.18 a12d4a773761187d80fa183d6f6b97d7 near ligand and helix rs17356051 GD 321 Q5VTX0 MSE SELENOMETHIONINE 15 20.45 1vjv A 0.81 2fdae70e5b219324f26bfa3411e04a0b near ligand and buried charge rs4237768 RW 282 Q8NGH7 RET RETINAL 15 15.38 1u19 A 0.05 537fea1c8ccb4a7ee146148432e89dab near ligand and buried charge rs10896310 MIT 206 Q8NH10 RET RETINAL 15 16.48 1u19 A 0.11 8efddbf698c5df22d560ef9f2399d437 near ligand and destabilizing rs140599 CY 1153 P35555 NAG N-ACETYLGLUCOSAMINE 15 15.38 1cvu A 0.02 553a835f3c25a20e75bd335202216583 near ligand and destabilizing rs17224674 RQ 166 Q8NGE0 ZN 15 16.49 1u19 A 0.09 5269ec4ffe9173c8e46c0e0a9fb48ed2 near ligand and buried charge rs10769224 CY 125 Q8NH53 HG 15 10.58 1u19 A 0.04 e452304dca195e5b51ad54b82e389eab near ligand and destabilizing rs11088674 NH 660 P98073 CA 15 33.33 1szb A 0.14 76974b39d6ccf500d7ec67d8694b1046 near ligand and buried charge rs4987233 SN 200 Q5VZI7 NAG N-ACETYLGLUCOSAMINE 15 10.53 1ozn A 1.00 dbe058cff844c1cf546e2f5f2b48db76 near ligand and destabilizing rs3738247 DE 288 Q9NR50-2 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 15 12 1yp2 A 0.15 b1176c0d3d3aacb60722cfbaba193122 near ligand and destabilizing rs17024904 PH 360 Q96NU7 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 15 17.39 1gkp A 1.00 30cc29114fdf4b69e871161a2daecdba near ligand and helix rs7935144 RC 154 Q9H346 ZN 15 15.89 1u19 A 0.04 33187fcad670f45f8f555a9b9567eb49 near ligand and buried charge rs16912062 GR 299 Q8NH94 HG 15 16.49 1u19 A 0.05 5642a99c69b259c0c45eb6792c495eb6 near ligand and buried charge rs17356051 GD 320 Q9UK80 MSE SELENOMETHIONINE 15 20.45 1vjv A 0.96 2df74ecc9f6a68ae7b3880c66dcf22ab near ligand and buried charge rs10896309 MIT 206 Q8NH10 ZN 15 16.48 1u19 A 0.11 8efddbf698c5df22d560ef9f2399d437 near ligand and destabilizing rs4987233 SN 400 Q5VZI7 NAG N-ACETYLGLUCOSAMINE 15 10.53 1ozn A 1.00 dbe058cff844c1cf546e2f5f2b48db76 near ligand and destabilizing rs10896309 MIT 206 Q8NH10 RET RETINAL 15 16.48 1u19 A 0.11 8efddbf698c5df22d560ef9f2399d437 near ligand and destabilizing rs10896310 MIT 206 Q8NH10 ZN 15 16.48 1u19 A 0.11 8efddbf698c5df22d560ef9f2399d437 near ligand and destabilizing rs17356051 GD 321 Q9UK80 MSE SELENOMETHIONINE 15 20.45 1vjv A 0.96 2df74ecc9f6a68ae7b3880c66dcf22ab near ligand and buried charge rs7101919 IT 251 Q9H346 RET RETINAL 15 15.89 1u19 A 0.04 33187fcad670f45f8f555a9b9567eb49 near ligand and destabilizing rs3738247 DE 288 Q9NR50-3 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 15 12 1yp2 A 0.30 67b568a03e4e5cca5f99e73b8503c880 near ligand and destabilizing rs17356051 GD 320 Q5VTX0 MSE SELENOMETHIONINE 15 20.45 1vjv A 0.81 2fdae70e5b219324f26bfa3411e04a0b near ligand and buried charge rs351260 AT 247 Q14154 MSE SELENOMETHIONINE 14 11.54 1xnf A 0.34 06216902a448e10d8aa085d0d05b9ed6 near ligand and destabilizing rs3747582 PL 252 Q9HBL8 GDP GUANOSINE DIPHOSPHATE 14 22.22 1n7h A 1.00 58025eb96744ee6a018f27e0217aa532 near ligand and helix rs17418077 GD 127 P18577-4 MSE SELENOMETHIONINE 14 11.54 1u7g A 0.02 76348552b677d227c05cdd5d3d49f900 near ligand and buried charge rs17418077 GD 112 P18577-4 MSE SELENOMETHIONINE 14 11.54 1u7g A 0.02 76348552b677d227c05cdd5d3d49f900 near ligand and buried charge rs1053347 GD 127 P18577-4 MSE SELENOMETHIONINE 14 11.54 1u7g A 0.02 76348552b677d227c05cdd5d3d49f900 near ligand and buried charge rs4985162 PL 301 Q6P996 PMP PYRIDOXAMINE PHOSPHATE 14 33.33 2gsa A 0.26 9a5019db8f045d33bb9aa06116818854 near ligand and helix rs3747582 PL 252 Q9HBL8 UD2 URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE 14 12.2 1sb8 A 1.00 81b82ae37f2102d1565531db999e39b4 near ligand and helix rs3177338 RC 425 Q96C13 PO4 PHOSPHATE GROUP, NEAR ACTIVE SITE 14 25.64 1ksh A 0.36 c4d17fa70f0f900e8049a184f35f65ff near ligand and desolubilizing rs6591324 CR 122 Q8NH85 HG 14 11.36 1u19 A 0.06 bb5e57ccc5fcdc210f5ac9f2ef64aedf near ligand and buried charge rs897738 DN 122 Q6ZMN0 CA 14 16.36 1n7d A 0.01 3784dac78f872b2c45493759089d97fb near ligand and buried charge rs628524 SN 171 Q96RB7 ZN 14 15.22 1u19 A 0.21 52edae97dd770755dbe770d201f48715 near ligand and destabilizing rs1053347 GD 112 P18577-4 MSE SELENOMETHIONINE 14 11.54 1u7g A 0.02 76348552b677d227c05cdd5d3d49f900 near ligand and buried charge rs897738 DN 174 Q6ZMN0 CA 14 16.36 1n7d A 0.01 3784dac78f872b2c45493759089d97fb near ligand and buried charge rs2296441 AT 533 Q9BRQ1 FAD FLAVIN-ADENINE DINUCLEOTIDE 13 14.86 1rsg A 0.82 5ec5fba0ebe3c2b04071e76b24603de2 near ligand and destabilizing rs20558 PL 888 P11047 HEC HEM C CONTAINING FE 13 16.18 1ofw A 0.01 fe4423426973627c50b655067a0f6630 near ligand and helix rs7410919 PL 888 P11047 HEC HEM C CONTAINING FE 13 16.18 1ofw A 0.01 fe4423426973627c50b655067a0f6630 near ligand and helix rs2292971 MT 617 Q9BRC2 MSE SELENOMETHIONINE 12 13.61 1qbk B 0.55 81f695a1750af1b3991ff0c74aa8141c near ligand and destabilizing rs3927729 PL 152 Q5VTG9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 b829d00fa7237b1911d80d26f23ecc5e near ligand and helix rs3927729 PL 152 Q7Z3S9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 0d35daeb4fe51dbf2d8c015e4fd848ed near ligand and helix rs17356051 GD 320 Q9HBS2 MSE SELENOMETHIONINE 12 15.66 1vjv A 0.31 4857f51be2583dd774b62e67337aae1f near ligand and buried charge rs3927729 PL 113 Q7Z3S9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 0d35daeb4fe51dbf2d8c015e4fd848ed near ligand and helix rs11090865 AS 10 O75648 ANP 5'-ADENYL-IMIDO-TRIPHOSPHATE 12 17.07 1kor A 0.34 f04c7ad1f1972cbf170f160dd3dd1ac3 near ligand and destabilizing rs3927729 PL 113 Q5VTG9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 b829d00fa7237b1911d80d26f23ecc5e near ligand and helix rs2292971 MT 71 Q9BRC2 MSE SELENOMETHIONINE 12 13.61 1qbk B 0.55 81f695a1750af1b3991ff0c74aa8141c near ligand and destabilizing rs951773 RC 446 Q9NSB2 NAG N-ACETYLGLUCOSAMINE 12 12.5 1m1j B 0.00 a27a6b6a37b710524c2db0170ecc272f near ligand and desolubilizing rs1866389 AP 387 P35443 NAG N-ACETYLGLUCOSAMINE 12 9.89 1n7d A 0.00 904b629cab97771389077b4a000595d3 near ligand and destabilizing rs3927729 PL 126 Q5BKT8 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 7241ad5bea0d06e9461ad0905ae82120 near ligand and helix rs3927729 PL 126 Q5VTG9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 b829d00fa7237b1911d80d26f23ecc5e near ligand and helix rs17884905 AP 387 P35443 NAG N-ACETYLGLUCOSAMINE 12 9.89 1n7d A 0.00 904b629cab97771389077b4a000595d3 near ligand and destabilizing rs17025464 SN 289 Q96BL6 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 12 20.69 1w5s A 0.10 d0bb87da4afb61f0a45b9fcf7b7150ad near ligand and destabilizing rs3927729 PL 126 Q7Z3S9 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 0d35daeb4fe51dbf2d8c015e4fd848ed near ligand and helix rs11574885 QR 300 P46531 CA 12 11.83 1n7d A 0.00 20f58b4fdc407a42bf010f3db0a56dbc near ligand and buried charge rs17356051 GD 321 Q9HBS2 MSE SELENOMETHIONINE 12 15.66 1vjv A 0.31 4857f51be2583dd774b62e67337aae1f near ligand and buried charge rs3927729 PL 152 Q5BKT8 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 7241ad5bea0d06e9461ad0905ae82120 near ligand and helix rs3748210 QK 126 P09466 DB1 2,3-DIHYDROXYBENZAMIDE 12 15.38 1x71 A 0.44 e30b19fa64082470ab6a12637f48747a near ligand and buried charge rs3927729 PL 113 Q5BKT8 ACD ARACHIDONIC ACID 12 7.69 1cvu A 0.01 7241ad5bea0d06e9461ad0905ae82120 near ligand and helix rs3748210 QK 126 P09466 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 12 14.81 1i4u A 0.39 5870f9a56bbfbc26bc3b77f0b01351c9 near ligand and buried charge rs9932912 AT 552 Q70CQ4 MSE SELENOMETHIONINE 11 13.21 1vjv A 0.10 805f56d87baa59d7ea956ee48b0557ae near ligand and destabilizing rs17416162 HQ 114 Q9TP69 MAN MANNOSIDE IN MONOMER D 11 13.89 1o0v A 0.09 a6ac816694b0af7926b8f82310082c71 near ligand and buried charge rs17052017 SN 456 P13196 GTP GUANOSINE TRIPHOSPHATE 11 33.33 1c4k A 0.21 987f9e45329614cc73d1aafb14223db4 near ligand and destabilizing rs17416162 HQ 117 Q9TP69 MAN MANNOSIDE IN MONOMER D 11 13.89 1o0v A 0.09 a6ac816694b0af7926b8f82310082c71 near ligand and buried charge rs17416162 HQ 114 P17693 MAN MANNOSIDE IN MONOMER D 11 13.89 1o0v A 0.23 496fca45d9fd7812a71284f2a76484c7 near ligand and buried charge rs4832168 GR 260 Q9NXE5 FAD FLAVIN-ADENINE DINUCLEOTIDE 11 20 1n4w A 0.07 8621ef92b8826d28a6f37444ac66d558 near ligand and buried charge rs13339649 IT 538 Q70CQ4 MSE SELENOMETHIONINE 11 13.21 1vjv A 0.10 805f56d87baa59d7ea956ee48b0557ae near ligand and destabilizing rs17416162 HQ 117 P17693 MAN MANNOSIDE IN MONOMER D 11 13.89 1o0v A 0.23 496fca45d9fd7812a71284f2a76484c7 near ligand and buried charge rs4832168 RQ 204 Q9NXE5 FAD FLAVIN-ADENINE DINUCLEOTIDE 11 20 1n4w A 0.07 8621ef92b8826d28a6f37444ac66d558 near ligand and buried charge rs6091654 KE 751 O43156 MSE SELENOMETHIONINE 11 15.43 1qbk B 0.50 1501949a9cdcb9daf4df6c2ecc8507e9 near ligand and buried charge rs458273 DH 496 Q9UL63 GLC BETA-D-GLUCOSE 10 7.41 1k3i A 0.19 494c8e311a28b49de6c60285afc10b4e near ligand and buried charge rs11881580 CR 310 Q6ZMY6 MES N-ETHYLSULFONIC ACID MORPHOLINE 10 33.33 2bkl A 0.05 70e95096ce3109e60ac9384d72b05b68 near ligand and desolubilizing rs11881580 RC 310 Q6ZMY6 MES N-ETHYLSULFONIC ACID MORPHOLINE 10 33.33 2bkl A 0.05 70e95096ce3109e60ac9384d72b05b68 near ligand and desolubilizing rs4818949 QP 129 P60014 ACD ARACHIDONIC ACID 10 11.54 1cvu A 0.00 06f772bab794f6c3c9a40252d36323e1 near ligand and helix rs2834167 KE 47 Q6ZVU9 NAG N-ACETYLGLUCOSAMINE 9 0 1gh7 A 0.00 ed10467f0e5d1fbeb2f8bae73981740c near ligand and buried charge rs2834167 EK 49 Q6ZVU9 NAG N-ACETYLGLUCOSAMINE 9 0 1gh7 A 0.00 ed10467f0e5d1fbeb2f8bae73981740c near ligand and buried charge rs696723 GR 713 Q5VVM9 CA 9 6.25 1n7d A 0.00 6936b30208ba002fbaca0dd47466e811 near ligand and buried charge rs2229481 RQ 1186 P98160 SO4 SULFATE ION, SULFUR ATOM ONLY GIVEN. 9 2.94 1igr A 0.00 350f121f4a556f63924ca31a3f5c2335 near ligand and buried charge rs4698803 VE 920 P01133 NAG N-ACETYLGLUCOSAMINE 9 0 1igr A 0.00 8a83f2b7eef927bd16b37946083d7993 near ligand and buried charge rs3821033 AT 1313 P52746 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 8 10.07 1fgj A 0.00 31e4afa3367ab2d5b539711d179d6be3 near ligand and destabilizing rs11670246 FS 270 Q03923 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 8 9.24 1fgj A 0.00 17e7fc96669226ec6f7641190d7b074a near ligand and destabilizing rs10407978 FS 490 Q68DY1 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 8 7.07 1fgj A 0.01 ca257d5618b5a6bbd31d2f20f3ad46ef near ligand and destabilizing rs9873604 IT 483 Q9P0L1 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 8 9.09 1fgj A 0.00 7b587115361c4e399cddf884bf376b20 near ligand and destabilizing rs3752153 RQ 379 P17017 HEC HEM C CONTAINING FE 8 12.21 1fgj A 0.00 4891d96bcfaceaf1022c289e633aca52 near ligand and buried charge rs16979670 TN 251 Q9BR84 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 8 10.17 1fgj A 0.00 465bbac7fad7c9a7049adc97b7db2a34 near ligand and destabilizing rs1974777 QR 682 Q8TEQ6 HEC HEM C CONTAINING FE 8 9.41 1kb0 A 0.02 03121f706d83c0581cf91a72e47d6c7c near ligand and buried charge rs10500210 RC 443 Q9H7R0 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 7 10.85 1fgj A 0.00 b8c55eb8bd8a04ae7925b6251ba24680 near ligand and desolubilizing rs435590 PA 337 Q9UK13 HEC HEM C CONTAINING FE 6 7.56 1fgj A 0.00 9b97cb6957ecaf7ef8b4bf69c8d13631 near ligand and helix rs7343858 PL 431 Q9Y3M9 HEC HEM C CONTAINING FE 6 6.67 1fgj A 0.00 1d7eef090e6f9829cdb483737ef377e0 near ligand and helix rs4802029 LH 573 Q7Z3V5 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 8.26 1fgj A 0.00 1e014e4b2af7cdc7fa091889227c8634 near ligand and buried charge rs1059199 EK 188 Q6V9R5 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 5.94 1fgj A 0.00 9591afd4bd8ae4151d4225c3224fd4aa near ligand and buried charge rs1059199 EK 188 Q9NXS5 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 5.94 1fgj A 0.00 3834c880f0cfef94e8e8d97744b3c36e near ligand and buried charge rs1059199 EK 260 Q9NXS5 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 5.94 1fgj A 0.00 3834c880f0cfef94e8e8d97744b3c36e near ligand and buried charge rs6509593 GD 352 Q9BS31 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 8.7 1fgj A 0.00 a6632b5034118905f016358180c89bdc near ligand and buried charge rs2195980 IT 244 Q8N7M2 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 6.78 1fgj A 0.00 1cd1bbb7fc275765b1617f84255860d9 near ligand and destabilizing rs1059199 EK 260 Q6V9R5 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 5.94 1fgj A 0.00 9591afd4bd8ae4151d4225c3224fd4aa near ligand and buried charge rs1060877 CS 310 Q9UIE0 HEM PROTOPORPHYRIN IX,REDCD VINYL GRPS, FE2 6 7.21 1fgj A 0.00 bfc10e3f9df4b401892346571013d6df near ligand and destabilizing rs2159940 EK 206 Q8TB69 HEC HEM C CONTAINING FE 5 6.56 1fgj A 0.00 661d90d6adb1cabc3cecd1d1fdd38c72 near ligand and buried charge