Structure Alignment Results.  

CRYSTAL STRUCTURE OF LANOSTEROL 14-ALPHA DEMETHYLASE WITH INTACT TRANSMEMBRANE DOMAIN BOUND TO ITRACONAZOLE

##	Scoring			RMSD	Nalign	Ng	%seq	Query	Target (PDB entry)
	Q	P	Z					%sse	Match	%sse	Nres	×	Title
1	1.00	134.9	35.1	0.00	531	0	100	100	4k0f:A	100	531		CRYSTAL STRUCTURE OF LANOSTEROL 14-ALPHA DEMETHYLASE WITH INTACT TRANSMEMBRANE DOMAIN BOUND TO ITRACONAZOLE
2	0.96	76.4	26.4	0.43	525	1	100	94	4lxj:A	100	530		SACCHAROMYCES CEREVISIAE LANOSTEROL 14-ALPHA DEMETHYLASE WITH LANOSTEROL BOUND
3	0.63	43.1	19.7	1.41	428	12	39	75	3ld6:A	83	445		CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH KETOCONAZOLE
4	0.63	41.4	19.3	1.42	428	12	39	72	3jus:A	82	445		CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH ECONAZOLE
5	0.61	41.8	19.7	1.40	420	16	39	72	3jus:B	82	445		CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51) IN COMPLEX WITH ECONAZOLE
6	0.56	37.8	18.7	1.53	411	13	38	72	3juv:A	92	448		CRYSTAL STRUCTURE OF HUMAN LANOSTEROL 14ALPHA-DEMETHYLASE (CYP51)
7	0.53	28.1	16.5	1.75	407	16	29	72	3k1o:A	85	442		CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH A POTENTIAL ANTICHAGASIC DRUG, POSACONAZOLE
8	0.52	25.6	15.8	1.88	415	16	28	72	3zg3:A	88	445		STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR N-(1-(5-( TRIFLUOROMETHYL)(PYRIDIN-2-YL))PIPERIDIN-4YL)-N-(4-( TRIFLUOROMETHYL)PHENYL)PYRIDIN-3-AMINE (EPL-BS967, UDD)
9	0.51	26.3	15.9	1.88	409	16	29	72	2wuz:B	85	444		X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE IN ALTERNATIVE CONFORMATION
10	0.51	23.1	15.6	1.79	405	17	30	72	3l4d:B	79	449		CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE
11	0.51	26.3	15.9	1.89	408	16	29	72	2wuz:A	85	444		X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA CRUZI IN COMPLEX WITH FLUCONAZOLE IN ALTERNATIVE CONFORMATION
12	0.50	27.2	16.2	1.89	407	16	28	72	2wv2:A	85	443		X-RAY STRUCTURE OF CYP51 FROM THE HUMAN PATHOGEN TRYPANOSOMA BRUCEI IN COMPLEX WITH FLUCONAZOLE
13	0.50	24.1	15.9	1.83	404	17	30	72	3l4d:D	79	445		CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE
14	0.50	23.2	15.5	1.86	407	19	28	72	3zg2:A	85	449		STEROL 14 ALPHA-DEMETHYLASE (CYP51) FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR (S)-2-(4-CHLOROPHENYL)-2- (PYRIDIN-3-YL)-1-(4-(4-(TRIFLUOROMETHYL)PHENYL)PIPERAZIN-1-YL) ETHANONE (EPL-BS1246,UDO)
15	0.50	22.1	15.3	1.92	410	16	30	72	3l4d:A	77	448		CRYSTAL STRUCTURE OF STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM LEISHMANIA INFANTUM IN COMPLEX WITH FLUCONAZOLE
16	0.50	24.8	15.5	1.83	401	17	28	72	2x2n:C	85	441		X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH POSACONAZOLE IN TWO DIFFERENT CONFORMATIONS
17	0.50	23.5	15.7	1.87	406	15	28	72	4g7g:C	77	448		STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(3,4'-DIFLUOROBIPHENYL-4-YL)-2-(1H- IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [VNI/VNF (VFV)]
18	0.50	22.8	15.5	1.97	411	17	29	72	4g7g:D	77	448		STEROL 14-ALPHA DEMETHYLASE (CYP51) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH THE VNI DERIVATIVE (R)-N-(1-(3,4'-DIFLUOROBIPHENYL-4-YL)-2-(1H- IMIDAZOL-1-YL)ETHYL)-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE [VNI/VNF (VFV)]
19	0.50	23.2	15.7	2.00	414	13	29	72	4bjk:C	79	450		CYP51 OF TRYPANOSOMA BRUCEI BOUND TO (S)-N-(3-(1H-INDOL-3- YL)-1-OXO-1-(PYRIDIN-4-YLAMINO)PROPAN-2-YL)-3,3'-DIFLUORO-( 1,1'-BIPHENYL)-4-CARBOXAMIDE
20	0.49	22.3	15.4	1.87	403	17	28	72	2x2n:D	79	447		X-RAY STRUCTURE OF CYP51 FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH POSACONAZOLE IN TWO DIFFERENT CONFORMATIONS