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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P06213
Original Database ID sp P06213
Organism Homo sapiens
Annotation recname: full=insulin receptor;short=ir;ec=2.7.10.1;altname:
cd_antigen=cd220;co ntains:recname:
full=insulin receptor subunit
alpha;contains:recname: ...
Sequence Length 1382
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs28933085 N489 NS  
rs28933083 K487 KE  
rs1051692 Y171 YH  
8 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2ahxcrystal structure of erbb4/her4 extracellular domain
DBALI2ahxA 
CATH3.80.20.20 Domain: 2ahxA01 24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'. Chain A, domain 1 (95%)
CATH2.10.220.10 Domain: 2ahxA02 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 (100%)
CATH3.80.20.20 Domain: 2ahxA03 24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'. Chain A, domain 1 (100%)
CATH2.10.220.10 Domain: 2ahxA04 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 (94%)
JenaImageLibrary2ahx 
Target Sequence
UniProtKBP06213RecName: Full=Insulin receptor;Short=IR;EC=2.7.10.1;AltName: CD_antigen=CD220;Contains:RecName: Full=Insulin receptor subunit alpha;Contains:RecName: Full=Insulin receptor subunit beta;Flags: Precurso
InterProP06213 
PFAMP06213 
ProdomP06213 
GenPept281052323Sequence 24 from patent US 7611703
GenPept33112647INSR_HUMAN Insulin receptor precursor (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta]