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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P29474
Original Database ID SN P29474_chr7:15012854
Organism Homo sapiens
Annotation nitric-oxide synthase, endothelial
(ec 1.14.13.39) (ec-nos) (nos
typede iii) ( nosiii) (endothelial
nos) (enos) (constitutive nos)
(cnos)
Sequence Length 1202
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs7792133 R664 RH  
rs3918232 V826 VM   X
rs3918201 R884 RM   X
rs3918234 Q981 QL   X
rs6947833 C990 CS   P
7 SNPs found but only 5 displayed. (SNPs in modeled regions)
 

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for NOS3
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1tllcrystal structure of rat neuronal nitric-oxide synthase reductase module at 2.3 a resolution.
DBALI1tllA 
CATH1.20.990.10 Domain: 1tllA02 NADPH-cytochrome p450 Reductase; Chain A, domain 3 (100%)
CATH2.40.30.10 Domain: 1tllA03 Translation factors (100%)
CATH3.40.50.80 Domain: 1tllA04 Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module (99%)
JenaImageLibrary1tll 
Target Sequence
UniProtKBP29474Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS typeDE III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS)
InterProP29474 
PFAMP29474 
ProdomP29474 
UCSCGenomeBrowserP29474