University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco

ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P29475.2
Original Database ID EN ENSP00000320758.6
Organism Homo sapiens
Annotation nos1_human recname: full=nitric
oxide synthase, brain; altname:
full=constitutiv e nos; altname:
full=nc-nos; altname: full=nos
type i; altname: full= ...
Sequence Length 1434
 

SNP Information

Perform action on this model:

 
 
SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs9658482 Q1064 QR  
rs9658445 G864 GD  
6 SNPs found but only 2 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for NP_000611 R48C
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1tllcrystal structure of rat neuronal nitric-oxide synthase reductase module at 2.3 a resolution.
DBALI1tllA 
CATH1.20.990.10 Domain: 1tllA02 NADPH-cytochrome p450 Reductase; Chain A, domain 3 (100%)
CATH2.40.30.10 Domain: 1tllA03 Translation factors (100%)
CATH3.40.50.80 Domain: 1tllA04 Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module (100%)
JenaImageLibrary1tll 
Target Sequence
UniProtKBE9PH30RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProE9PH30 
PFAME9PH30 
ProdomE9PH30 
UniProtKBP29475RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProP29475 
PFAMP29475 
ProdomP29475 
UniProtKBB3VK56RecName: Full=Nitric oxide synthase {ECO:0000256|PIRNR:PIRNR000333};EC=1.14.13.39 {ECO:0000256|PIRNR:PIRNR000333};
InterProB3VK56 
PFAMB3VK56 
ProdomB3VK56 
UniProtKBO75713RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProO75713 
PFAMO75713 
ProdomO75713 
UniProtKBB3VK56RecName: Full=Nitric oxide synthase;EC=1.14.13.39;
InterProB3VK56 
PFAMB3VK56 
ProdomB3VK56 
UniProtKBP29475.2NOS1_HUMAN RecName: Full=Nitric oxide synthase, brain; AltName: Full=Constitutive NOS; AltName: Full=NC-NOS; AltName: Full=NOS type I; AltName: Full=Neuronal NOS; Short=N-NOS; Short=nNOS; AltName: Ful
InterProP29475.2 
PFAMP29475.2 
ProdomP29475.2 
UniProtKBE9PH30RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProE9PH30 
PFAME9PH30 
ProdomE9PH30 
UniProtKBO75713RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProO75713 
PFAMO75713 
ProdomO75713 
UniProtKBP29475RecName: Full=Nitric oxide synthase, brain;EC=1.14.13.39;AltName: Full=Constitutive NOS;AltName: Full=NC-NOS;AltName: Full=NOS type I;AltName: Full=Neuronal NOS;Short=N-NOS;Short=nNOS;AltName: Full=Pe
InterProP29475 
PFAMP29475 
ProdomP29475 
RefSeqNP_000611.1 nitric oxide synthase, brain [Homo sapiens]
GenPept987662nitric oxide synthase
GenPept642526neuronal nitric oxide synthase
GenPept5979686Sequence 19 from patent US 5834306
GenPept568534782Sequence 22407 from patent US 8586006
GenPept53972022Sequence 1034 from patent US 6753314
GenPept40141578Sequence 1 from patent US 6620616
GenPept192335157NOS1 mutant
GenPept1709333NOS1_HUMAN RecName: Full=Nitric oxide synthase, brain; AltName: Full=Constitutive NOS; AltName: Full=NC-NOS; AltName: Full=NOS type I; AltName: Full=Neuronal NOS; Short=N-NOS; Short=nNOS; AltName: Ful
GenPept162317690Nitric oxide synthase 1 (neuronal), partial
GenPept15110428Sequence 19 from patent US 6218179
GenPept14764337 nitric oxide synthase 1 (neuronal) [Homo sapiens]
GenPept14764331 nitric oxide synthase 1 (neuronal) [Homo sapiens]
GenPept119618516nitric oxide synthase 1 (neuronal), isoform CRA_c
GenPept11435003 nitric oxide synthase 1 (neuronal) [Homo sapiens]
GenPept2135826I56508 nitric-oxide synthase (EC 1.14.13.39) - human
GenPept10835173 nitric oxide synthase, brain isoform 1 [Homo sapiens]
GenPept37999981nitric oxide synthase 1 (neuronal)
GenPept314882909Sequence 3151 from patent US 7842467
GenPept314882908Sequence 3150 from patent US 7842467
GenPept225000214Nitric oxide synthase 1 (neuronal)
GenBankAAA62405.1 neuronal nitric oxide synthase [Homo sapiens]
GenBankEAW98110.1 nitric oxide synthase 1 (neuronal), isoform CRA_c [Homo sapiens]
GenBankAAI56400.1 Nitric oxide synthase 1 (neuronal) [synthetic construct]
GenBankAAI72474.1 Nitric oxide synthase 1 (neuronal) [synthetic construct]
GenBankAAR07069.1 nitric oxide synthase 1 (neuronal) [Homo sapiens]
GenBankACF04132.1 NOS1 mutant [Homo sapiens]
UCSCGenomeBrowserP29475 
ENSEMBLENSP00000320758