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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link B7Z955
Original Database ID EN ENSP00000369100.4
Organism Gorilla gorilla gorilla, Pan paniscus, etc.
Annotation recname: full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
3;short=6pf-2 -k/fru-2,6-p2ase
3;short=pfk/fbpase 3;altname:
full=6pf-2-k/fru-2,6-p ...
Sequence Length 520

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

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Target Region26-447
Protein Length520
Template PDB Code5hr5A
Template Region30-451
Sequence Identity75%
E-Value0
GA3411
MPQS1.81054
z-DOPE-1.57
TSVMod MethodMSALL
TSVMod RMSD1.024
TSVMod NO350.945
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB5hr5
DBALI5hr5A 
JenaImageLibrary5hr5 
Target Sequence
UniProtKBQ5VX19RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ5VX19 
PFAMQ5VX19 
ProdomQ5VX19 
UniProtKBO75902RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProO75902 
PFAMO75902 
ProdomO75902 
UniProtKBK7AP42SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 {ECO:0000313|EMBL:JAA19631.1};
InterProK7AP42 
PFAMK7AP42 
ProdomK7AP42 
UniProtKBO43622RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProO43622 
PFAMO43622 
ProdomO43622 
UniProtKBQ16875RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ16875 
PFAMQ16875 
ProdomQ16875 
UniProtKBQ5VX18SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3, isoform CRA_b;SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase;EC=3.1.3.46;SubName: Full=cDNA FLJ75111, highly
InterProQ5VX18 
PFAMQ5VX18 
ProdomQ5VX18 
UniProtKBA0A2I2ZVY76-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2I2ZVY7 
PFAMA0A2I2ZVY7 
ProdomA0A2I2ZVY7 
UniProtKBA0A2J8KTN26-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2J8KTN2 
PFAMA0A2J8KTN2 
ProdomA0A2J8KTN2 
UniProtKBA0A2J8VK626-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2J8VK62 
PFAMA0A2J8VK62 
ProdomA0A2J8VK62 
UniProtKBA0A2R8ZUU56-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2R8ZUU5 
PFAMA0A2R8ZUU5 
ProdomA0A2R8ZUU5 
UniProtKBA0A6D2VT166-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A6D2VT16 
PFAMA0A6D2VT16 
ProdomA0A6D2VT16 
UniProtKBA0A8I5TFL5SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSPPYP00000035958}
InterProA0A8I5TFL5 
PFAMA0A8I5TFL5 
ProdomA0A8I5TFL5 
UniProtKBQ5VX18SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3, isoform CRA_b;SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase;EC=3.1.3.46;SubName: Full=6-phosphofructo-2-kina
InterProQ5VX18 
PFAMQ5VX18 
ProdomQ5VX18 
UniProtKBQ16875.1F263_HUMAN RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; Short=6PF-2-K/Fru-2,6-P2ase 3; Short=PFK/FBPase 3; AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; AltN
InterProQ16875.1 
PFAMQ16875.1 
ProdomQ16875.1 
UniProtKBO75902RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProO75902 
PFAMO75902 
ProdomO75902 
UniProtKBQ16875RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ16875 
PFAMQ16875 
ProdomQ16875 
UniProtKBB7Z955RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProB7Z955 
PFAMB7Z955 
ProdomB7Z955 
UniProtKBQ5VX19RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ5VX19 
PFAMQ5VX19 
ProdomQ5VX19 
UniProtKBQ5VX15RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ5VX15 
PFAMQ5VX15 
ProdomQ5VX15 
UniProtKBO43622RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProO43622 
PFAMO43622 
ProdomO43622 
UniProtKBQ5VX18RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;Short=6PF-2-K/Fru-2,6-P2ase 3;Short=PFK/FBPase 3;AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;AltName: Full=Rena
InterProQ5VX18 
PFAMQ5VX18 
ProdomQ5VX18 
RefSeqNP_004557.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 isoform 1 [Homo sapiens]
RefSeqXP_024108821.16-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1
2208342A2208342A fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase
PDB5AJVBChain B, Human Pfkfb3 In Complex With An Indole Inhibitor 1
PDB5AJWAChain A, Human Pfkfb3 In Complex With An Indole Inhibitor 2
PDB5AJXAChain A, Human Pfkfb3 In Complex With An Indole Inhibitor 3
PDB5AJYAChain A, Human Pfkfb3 In Complex With An Indole Inhibitor 4
PDB5AJZAChain A, Human Pfkfb3 In Complex With An Indole Inhibitor 5
PDB4MA4AChain A, S-glutathionylated Pfkfb3
PDB5AK0AChain A, Human Pfkfb3 In Complex With An Indole Inhibitor 6
PDB3QPWAChain A, Pfkfb3 In Complex With Aluminum Tetrafluoride
PDB2DWPA Chain A, A Pseudo Substrate Complex Of 6-Phosphofructo-2-Kinase Of Pfkfb
PDB2DWPAChain A, A Pseudo Substrate Complex Of 6-Phosphofructo-2-Kinase Of Pfkfb
PDB2DWOAChain A, Pfkfb3 In Complex With Adp And Pep
PDB2DWOA Chain A, Pfkfb3 In Complex With Adp And Pep
PDB2AXNAChain A, Crystal Structure Of The Human Inducible Form 6- Phosphofructo-2-KinaseFRUCTOSE-2,6-Bisphosphatase
PDB2AXNA Chain A, Crystal Structure Of The Human Inducible Form 6- Phosphofructo-2-KinaseFRUCTOSE-2,6-Bisphosphatase
PDB2I1VB Chain B, Crystal Structure Of Pfkfb3 In Complex With Adp And Fructose-2,6-Bisphosphate
PDB3QPUAChain A, Pfkfb3 In Complex With Ppi
PDB3QPVAChain A, Pfkfb3 Trapped In A Phospho-Enzyme Intermediate State
PDB2I1VBChain B, Crystal Structure Of Pfkfb3 In Complex With Adp And Fructose-2,6-Bisphosphate
GenPept158255962unnamed protein product
GenPept83754166A Chain A, Crystal Structure Of The Human Inducible Form 6- Phosphofructo-2-KinaseFRUCTOSE-2,6-Bisphosphatase
GenPept1196068056-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, isoform CRA_b
GenPept14689166-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase
GenPept151566474A Chain A, Pfkfb3 In Complex With Adp And Pep
GenPept151566475A Chain A, A Pseudo Substrate Complex Of 6-Phosphofructo-2-Kinase Of Pfkfb
GenPept151567655B Chain B, Crystal Structure Of Pfkfb3 In Complex With Adp And Fructose-2,6-Bisphosphate
GenPept27289021Sequence 2 from patent US 6472516
GenPept262517696-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
GenPept223088502Sequence 6518 from patent US 6812339
GenPept15883252208342A fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase
GenPept17467090L77662_1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
GenPept1196068046-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, isoform CRA_b
GenPept3023733F263_HUMAN RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; Short=6PF-2-K/Fru-2,6-P2ase 3; Short=PFK/FBPase 3; AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; AltN
GenPept810516788B Chain B, Human Pfkfb3 In Complex With An Indole Inhibitor 1
GenPept649151062PFKFB3, partial
GenPept649102063PFKFB3, partial
GenPept374977561A Chain A, Pfkfb3 Trapped In A Phospho-Enzyme Intermediate State
GenPept374977562A Chain A, Pfkfb3 In Complex With Aluminum Tetrafluoride
GenPept4758900 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 isoform 1 [Homo sapiens]
GenPept4165896ubiquitous 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase
GenPept564731177A Chain A, S-glutathionylated Pfkfb3
GenPept556646376-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
GenPept556620756-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
GenPept53972349Sequence 1361 from patent US 6753314
GenPept810516790A Chain A, Human Pfkfb3 In Complex With An Indole Inhibitor 2
GenPept810516792A Chain A, Human Pfkfb3 In Complex With An Indole Inhibitor 3
GenPept810516794A Chain A, Human Pfkfb3 In Complex With An Indole Inhibitor 4
GenPept3138825186-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), transcript variant 1, partial
GenPept374977560A Chain A, Pfkfb3 In Complex With Ppi
GenPept810516840A Chain A, Human Pfkfb3 In Complex With An Indole Inhibitor 6
GenPept810516796A Chain A, Human Pfkfb3 In Complex With An Indole Inhibitor 5
GenBankEAW86398.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, isoform CRA_b [Homo sapiens]
GenBankEAW86399.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, isoform CRA_b [Homo sapiens]
GenBankAAL40083.1L77662_1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase [Homo sapiens]
GenBankAAH40482.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [Homo sapiens]
GenBankAAD08818.1 ubiquitous 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase [Homo sapiens]
ENSEMBLENSP000003211496-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC
EMBLCAH73607.1 
EMBLCAH72164.1 
ENSEMBLENSP00000321149 
ENSEMBLENSP00000321149TDI sequence
ENSEMBLENSP00000369100 
UCSCGenomeBrowserQ16875