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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link Q9NQR1.3
Original Database ID SN Q9NQR1_chr12:1223984
Organism Homo sapiens
Annotation setd8_human recname: full=histone-lysine
n-methyltransferase setd8; altname:
ful l=h4-k20-hmtase setd8; altname:
full=lysine n-methyltransferase
5a; a ...
Sequence Length 393
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs2270053 R279 RP   X
rs17854620 P357 PR  

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Cross-references

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Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1zkkcrystal structure of hset8 in ternary complex with h4 peptide (16-24) and adohcy
DBALI1zkkA 
JenaImageLibrary1zkk 
Target Sequence
UniProtKBQ9NQR1RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ9NQR1 
PFAMQ9NQR1 
ProdomQ9NQR1 
UniProtKBA8K9D0RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProA8K9D0 
PFAMA8K9D0 
ProdomA8K9D0 
UniProtKBQ86W83RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ86W83 
PFAMQ86W83 
ProdomQ86W83 
UniProtKBQ8TD09RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ8TD09 
PFAMQ8TD09 
ProdomQ8TD09 
UniProtKBQ9NQR1.3SETD8_HUMAN RecName: Full=Histone-lysine N-methyltransferase SETD8; AltName: Full=H4-K20-HMTase SETD8; AltName: Full=Lysine N-methyltransferase 5A; AltName: Full=PR/SET domain-containing protein 07; S
InterProQ9NQR1.3 
PFAMQ9NQR1.3 
ProdomQ9NQR1.3 
UniProtKBQ9NQR1RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ9NQR1 
PFAMQ9NQR1 
ProdomQ9NQR1 
UniProtKBQ8TD09RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ8TD09 
PFAMQ8TD09 
ProdomQ8TD09 
UniProtKBQ86W83RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProQ86W83 
PFAMQ86W83 
ProdomQ86W83 
UniProtKBA8K9D0RecName: Full=N-lysine methyltransferase SETD8;EC=2.1.1.-;AltName: Full=H4-K20-HMTase SETD8;AltName: Full=Histone-lysine N-methyltransferase SETD8;EC=2.1.1.43;AltName: Full=Lysine N-methyltransferase
InterProA8K9D0 
PFAMA8K9D0 
ProdomA8K9D0 
GenPept25091219SETD8_HUMAN RecName: Full=Histone-lysine N-methyltransferase SETD8; AltName: Full=H4-K20-HMTase SETD8; AltName: Full=Lysine N-methyltransferase 5A; AltName: Full=PR/SET domain-containing protein 07; S