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Sequence Information

Primary Database Link P36897
Original Database ID EN ENSP00000364133.4
Organism Homo sapiens, Mus musculus
Annotation recname: full=tgf-beta receptor
type-1;short=tgfr-1;ec=2.7.11.30;altname:
full=a ctivin a receptor type
ii-like protein kinase of 53kd;altname:
full=a ...
Sequence Length 503

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region175-500
Protein Length503
Template PDB Code1b6cB
Template Region175-500
Sequence Identity100%
E-Value0
GA3411
MPQS1.82071
z-DOPE-1.39
TSVMod MethodMTALL
TSVMod RMSD0.199
TSVMod NO351
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB1b6ccrystal structure of the cytoplasmic domain of the type i tgf-beta receptor in complex with fkbp12 ; EC: 2.7.1.37 5.2.1.8 ; PFAM: PF00069 PF00254 ; SCOP: 41673
DBALI1b6cB 
CATH3.30.200.20 Domain: 1b6cB01 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 1b6cB02 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary1b6c 
Target Sequence
UniProtKBQ5T7S2RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00138132};EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00138132};
InterProQ5T7S2 
PFAMQ5T7S2 
ProdomQ5T7S2 
UniProtKBQ706C0RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ706C0 
PFAMQ706C0 
ProdomQ706C0 
UniProtKBP36897RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProP36897 
PFAMP36897 
ProdomP36897 
UniProtKBQ6IR47RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ6IR47 
PFAMQ6IR47 
ProdomQ6IR47 
UniProtKBQ706C1RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ706C1 
PFAMQ706C1 
ProdomQ706C1 
UniProtKBQ5T7S2SubName: Full=Transforming growth factor beta receptor I;SubName: Full=Transforming growth factor, beta receptor 1;SubName: Full=Transforming growth factor, beta receptor I (Activin A receptor type II
InterProQ5T7S2 
PFAMQ5T7S2 
ProdomQ5T7S2 
UniProtKBP36897.1TGFR1_HUMAN RecName: Full=TGF-beta receptor type-1; Short=TGFR-1; AltName: Full=Activin receptor-like kinase 5; Short=ALK-5; AltName: Full=Serine/threonine-protein kinase receptor R4; Short=SKR4; AltN
InterProP36897.1 
PFAMP36897.1 
ProdomP36897.1 
UniProtKBQ706C1RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ706C1 
PFAMQ706C1 
ProdomQ706C1 
UniProtKBQ6IR47RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ6IR47 
PFAMQ6IR47 
ProdomQ6IR47 
UniProtKBQ706C0RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProQ706C0 
PFAMQ706C0 
ProdomQ706C0 
UniProtKBP36897RecName: Full=TGF-beta receptor type-1;Short=TGFR-1;EC=2.7.11.30;AltName: Full=Activin A receptor type II-like protein kinase of 53kD;AltName: Full=Activin receptor-like kinase 5;Short=ALK-5;Short=ALK
InterProP36897 
PFAMP36897 
ProdomP36897 
RefSeqNP_004603.1 TGF-beta receptor type-1 isoform 1 precursor [Homo sapiens]
GenPept223088512Sequence 6528 from patent US 6812339
GenPept547777TGFR1_HUMAN RecName: Full=TGF-beta receptor type-1; Short=TGFR-1; AltName: Full=Activin receptor-like kinase 5; Short=ALK-5; AltName: Full=Serine/threonine-protein kinase receptor R4; Short=SKR4; AltN
GenPept55958234transforming growth factor, beta receptor 1
GenPept568529449Sequence 6635 from patent US 8586006
GenPept756322269Sequence 148 from patent US 8680041
GenPept756656115Sequence 61 from patent US 8791112
GenPept757923496Sequence 1 from patent US 8603818
GenPept757923497Sequence 2 from patent US 8603818
GenPept88604813transforming growth factor beta receptor I
GenPept91133273Sequence 10 from patent US 6982319
GenPept4759226 TGF-beta receptor type-1 isoform 1 precursor [Homo sapiens]
GenPept431035activin receptor-like kinase
GenPept42714399Sequence 10 from patent US 6692925
GenPept119579310transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa), isoform CRA_a
GenPept14484803Sequence 10 from patent US 6207814
GenPept155076348Sequence 61 from patent US 7202033
GenPept16237306Sequence 10 from patent US 6271365
GenPept168277402TGF-beta receptor type-1 precursor, partial
GenPept28076479Sequence 10 from patent US 6331621
GenPept2295244unnamed protein product
GenPept254257711unnamed protein product
GenPept270048020transforming growth factor, beta receptor 1
GenPept119579309transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa), isoform CRA_a
GenPept1082168A49432 activin receptor-like kinase 5 precursor - human
GenPept414909683Sequence 2 from patent US 8298825
GenPept414909682Sequence 1 from patent US 8298825
GenPept4104447transforming growth factor-beta type I receptor
GenPept39843079transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
GenPept367487373Sequence 10 from patent US 8080639
GenPept348637567Sequence 10 from patent US 8012704
GenPept333649300Sequence 10 from patent US 7932351
GenPept314581105Sequence 42 from patent US 7816082
GenPept3003038TGF-beta type I receptor
GenPept259403090Sequence 10 from patent US 7592428
GenBankAAR32097.1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) [Homo sapiens]
GenBankEAW58906.1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa), isoform CRA_a [Homo sapiens]
GenBankEAW58905.1 transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa), isoform CRA_a [Homo sapiens]
GenBankACZ58375.1 transforming growth factor, beta receptor 1 [Homo sapiens]
GenBankABD46753.1 transforming growth factor beta receptor I [Homo sapiens]
GenBankAAA16073.1 activin receptor-like kinase [Homo sapiens]
GenBankAAD02042.1 transforming growth factor-beta type I receptor [Homo sapiens]
GenBankAAC08998.1 TGF-beta type I receptor [Homo sapiens]
ENSEMBLENSP00000262458TGF-beta receptor type I precursor (EC 2.7.1.37) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5). [Homo sapiens]
EMBLCAI17140.1 
UCSCGenomeBrowserP36897 
ENSEMBLENSP00000262458 
ENSEMBLENSP00000262458TDI sequence
ENSEMBLENSP00000364133