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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link D3DTR4
Original Database ID sp Q96GD4
Organism Homo sapiens, synthetic construct
Annotation subname: full=aurora kinase b,
isoform cra_c;
Sequence Length 344
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs1059476 T298 TM   X
rs17433751 T298 TM   X
rs3027254 H100 HQ  

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2vgpcrystal structure of aurora b kinase in complex with a aminothiazole inhibitor
DBALI2vgpB 
CATH3.30.200.20 Domain: 2vgpB01 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 2vgpB02 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary2vgp 
Target Sequence
UniProtKBD3DTR4SubName: Full=Aurora kinase B, isoform CRA_c;
InterProD3DTR4 
PFAMD3DTR4 
ProdomD3DTR4 
UniProtKBO60446AURORA-related kinase 2 (Serine/threonine kinase 12)
InterProO60446 
PFAMO60446 
ProdomO60446 
UniProtKBQ96GD4.2AURKB_HUMAN RecName: Full=Serine/threonine-protein kinase 12; AltName: Full=Aurora kinase B; AltName: Full=Aurora- and IPL1-like midbody-associated protein 1; Short=AIM-1; AltName: Full=Aurora/IPL1-re
InterProQ96GD4.2 
PFAMQ96GD4.2 
ProdomQ96GD4.2 
UniProtKBQ9UQ46RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProQ9UQ46 
PFAMQ9UQ46 
ProdomQ9UQ46 
UniProtKBO14630RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProO14630 
PFAMO14630 
ProdomO14630 
UniProtKBO60446RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProO60446 
PFAMO60446 
ProdomO60446 
UniProtKBO95083RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProO95083 
PFAMO95083 
ProdomO95083 
UniProtKBQ96DV5RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProQ96DV5 
PFAMQ96DV5 
ProdomQ96DV5 
UniProtKBQ96GD4RecName: Full=Serine/threonine-protein kinase 12;EC=2.7.11.1;AltName: Full=Aurora kinase B;AltName: Full=Serine/threonine-protein kinase aurora-B;AltName: Full=Aurora- and IPL1-like midbody-associated
InterProQ96GD4 
PFAMQ96GD4 
ProdomQ96GD4 
GenPept363837774Sequence 3 from patent US 8071297
GenPept47259848Sequence 3 from patent US 6716575
GenPept4759178 serine/threonine kinase 12 [Homo sapiens]
GenPept51593788Aurora kinase B
GenPept54695938serine/threonine kinase 12
GenPept550869588Sequence 2 from patent US 8552018
GenPept59766492Sequence 3 from patent US 6841579
GenPept61355604aurora kinase B
GenPept915754458Sequence 2 from patent US 8999988
GenPept119610483aurora kinase B, isoform CRA_c
GenPept358782748Sequence 214 from patent US 8062892
GenPept3402293aurora and IPL1-like midbody-associated protein kinase-1
GenPept119610484aurora kinase B, isoform CRA_c
GenPept127796234Aurora kinase B
GenPept14484180Sequence 3 from patent US 6207401
GenPept119610481aurora kinase B, isoform CRA_c
GenPept118822064Sequence 214 from patent US 7125663
GenPept118770491Sequence 3 from patent US 7119174
GenPept10056283Sequence 3 from patent US 5972676
GenPept10052916Sequence 3 from patent US 5962312
GenPept144994915Sequence 101 from patent US 7189507
GenPept167237996Sequence 2 from patent US 7312226
GenPept167340559Sequence 2 from patent US 7326712
GenPept167340570Sequence 2 from patent US 7326713
GenPept182928149Sequence 2 from patent US 7335662
GenPept261859330aurora kinase B, partial
GenPept27805737AURKB_HUMAN RecName: Full=Serine/threonine-protein kinase 12; AltName: Full=Aurora kinase B; AltName: Full=Aurora- and IPL1-like midbody-associated protein 1; Short=AIM-1; AltName: Full=Aurora/IPL1-re
GenPept2979630aurora-related kinase 2
GenPept314894287Sequence 214 from patent US 7846737
GenPept12653347serine/threonine kinase 12
GenBankEAW90078.1 aurora kinase B, isoform CRA_c [Homo sapiens]
GenBankEAW90077.1 aurora kinase B, isoform CRA_c [Homo sapiens]
GenBankAAX41156.1 aurora kinase B [synthetic construct]
GenBankAAV38341.1 serine/threonine kinase 12 [Homo sapiens]
GenBankAAH80581.1 Aurora kinase B [Homo sapiens]
GenBankAAH00442.3 Aurora kinase B [Homo sapiens]
GenBankAAC12709.1 aurora-related kinase 2 [Homo sapiens]
GenBankEAW90075.1 aurora kinase B, isoform CRA_c [Homo sapiens]